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Changes in hospital mortality in patients with cancer during the COVID-19 pandemic (ISARIC-CCP-UK): a prospective, multicentre cohort study.
Turtle L, Elliot S, Drake TM, Thorpe M, Khoury EG, Greenhalf W, Hardwick HE, Leeming G, Law A, Oosthuyzen W, Pius R, Shaw CA, Baillie JK, Openshaw PJM, Docherty AB, Semple MG, Harrison EM, Palmieri C; ISARIC4C Investigators. Turtle L, et al. Among authors: openshaw pjm. Lancet Oncol. 2024 May;25(5):636-648. doi: 10.1016/S1470-2045(24)00107-4. Epub 2024 Apr 12. Lancet Oncol. 2024. PMID: 38621404 Free article.
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.
Liew F, Efstathiou C, Fontanella S, Richardson M, Saunders R, Swieboda D, Sidhu JK, Ascough S, Moore SC, Mohamed N, Nunag J, King C, Leavy OC, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Harris VC, Houchen-Wolloff L, Greening NJ, Lone NI, Thorpe M, Thompson AAR, Rowland-Jones SL, Docherty AB, Chalmers JD, Ho LP, Horsley A, Raman B, Poinasamy K, Marks M, Kon OM, Howard LS, Wootton DG, Quint JK, de Silva TI, Ho A, Chiu C, Harrison EM, Greenhalf W, Baillie JK, Semple MG, Turtle L, Evans RA, Wain LV, Brightling C, Thwaites RS, Openshaw PJM; PHOSP-COVID collaborative group; ISARIC investigators. Liew F, et al. Among authors: openshaw pjm. Nat Immunol. 2024 Apr;25(4):607-621. doi: 10.1038/s41590-024-01778-0. Epub 2024 Apr 8. Nat Immunol. 2024. PMID: 38589621 Free PMC article.
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Wood GK, Collie C, Digby R, Ren A, Norton E, Leibowitz M, Ebrahimi S, Fower A, Fox H, Tato E, Ellul MA, Sunderland G, Held M, Hetherington C, Egbe FN, Palmos A, Stirrups K, Grundmann A, Chiollaz AC, Sanchez JC, Stewart JP, Griffiths M, Solomon T, Breen G, Coles AJ, Kingston N, Bradley JR, Chinnery PF, Cavanagh J, Irani SR, Vincent A, Baillie JK, Openshaw PJ, Semple MG; ISARIC4C Investigators; COVID-CNS Consortium; Taams LS, Menon DK. Michael BD, et al. Among authors: openshaw pj. Nat Commun. 2024 Apr 4;15(1):2918. doi: 10.1038/s41467-024-47320-6. Nat Commun. 2024. PMID: 38575615 Free PMC article. No abstract available.
RSV-related Community COPD Exacerbations and Novel Diagnostics: A Binational Prospective Cohort Study.
Wiseman DJ, Thwaites RS, Ritchie AI, Finney L, Macleod M, Kamal F, Shahbakhti H, van Smoorenburg LH, Kerstjens HA, Wildenbeest J, Öner D, Aerssens J, Berbers G, Schepp R, Uruchurtu A, Ditz B, Bont L, Allinson JP, van den Berge M, Donaldson GC, Openshaw PJ, Wedzicha J; RESCEU Investigators. Wiseman DJ, et al. Among authors: openshaw pj. Am J Respir Crit Care Med. 2024 Mar 19. doi: 10.1164/rccm.202308-1320OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38502541
Targeted metagenomics reveals association between severity and pathogen co-detection in infants with respiratory syncytial virus.
Lin GL, Drysdale SB, Snape MD, O'Connor D, Brown A, MacIntyre-Cockett G, Mellado-Gomez E, de Cesare M, Ansari MA, Bonsall D, Bray JE, Jolley KA, Bowden R, Aerssens J, Bont L, Openshaw PJM, Martinon-Torres F, Nair H, Golubchik T, Pollard AJ; RESCEU Consortium. Lin GL, et al. Among authors: openshaw pjm. Nat Commun. 2024 Mar 16;15(1):2379. doi: 10.1038/s41467-024-46648-3. Nat Commun. 2024. PMID: 38493135 Free PMC article.
Reframing sepsis immunobiology for translation: towards informative subtyping and targeted immunomodulatory therapies.
Shankar-Hari M, Calandra T, Soares MP, Bauer M, Wiersinga WJ, Prescott HC, Knight JC, Baillie KJ, Bos LDJ, Derde LPG, Finfer S, Hotchkiss RS, Marshall J, Openshaw PJM, Seymour CW, Venet F, Vincent JL, Le Tourneau C, Maitland-van der Zee AH, McInnes IB, van der Poll T. Shankar-Hari M, et al. Among authors: openshaw pjm. Lancet Respir Med. 2024 Apr;12(4):323-336. doi: 10.1016/S2213-2600(23)00468-X. Epub 2024 Feb 23. Lancet Respir Med. 2024. PMID: 38408467 Free PMC article. Review.
Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults.
Wagstaffe HR, Thwaites RS, Reynaldi A, Sidhu JK, McKendry R, Ascough S, Papargyris L, Collins AM, Xu J, Lemm NM, Siggins MK, Chain BM, Killingley B, Kalinova M, Mann A, Catchpole A, Davenport MP, Openshaw PJM, Chiu C. Wagstaffe HR, et al. Among authors: openshaw pjm. Sci Immunol. 2024 Sep 2;9(92):eadj9285. doi: 10.1126/sciimmunol.adj9285. Epub 2024 Feb 9. Sci Immunol. 2024. PMID: 38335268
A Genome-Wide Association Study of Respiratory Syncytial Virus Infection Severity in Infants.
Johnson M, Chelysheva I, Öner D, McGinley J, Lin GL, O'Connor D, Robinson H, Drysdale SB, Gammin E, Vernon S, Muller J, Wolfenden H, Westcar S, Anguvaa L, Thwaites RS, Bont L, Wildenbeest J, Martinón-Torres F, Aerssens J, Openshaw PJM, Pollard AJ. Johnson M, et al. Among authors: openshaw pjm. J Infect Dis. 2024 Mar 1;229(Supplement_1):S112-S119. doi: 10.1093/infdis/jiae029. J Infect Dis. 2024. PMID: 38271230
Enrichment of SARS-CoV-2 sequence from nasopharyngeal swabs whilst identifying the nasal microbiome.
Alrezaihi A, Penrice-Randal R, Dong X, Prince T, Randle N, Semple MG, Openshaw PJM; ISARIC4C Investigators; MacGill T, Myers T, Orr R, Zakotnik S, Suljič A, Avšič-Županc T, Petrovec M, Korva M, AlJabr W, Hiscox JA. Alrezaihi A, et al. Among authors: openshaw pjm. J Clin Virol. 2024 Apr;171:105620. doi: 10.1016/j.jcv.2023.105620. Epub 2023 Nov 25. J Clin Virol. 2024. PMID: 38237303
Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury.
Taquet M, Skorniewska Z, Zetterberg H, Geddes JR, Mummery CJ, Chalmers JD, Ho LP, Horsley A, Marks M, Poinasamy K, Raman B, Leavy OC, Richardson M, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC, Houchen-Wolloff L, Mansoori P, Greening NJ, Harrison EM, Docherty AB, Lone NI, Quint J, Greenhalf W, Wain LV, Brightling CE, Evans RE, Harrison PJ, Koychev I; PHOSP-COVID Study Collaborative Group. Taquet M, et al. Brain Commun. 2023 Dec 27;6(1):fcad357. doi: 10.1093/braincomms/fcad357. eCollection 2024. Brain Commun. 2023. PMID: 38229877 Free PMC article.
277 results