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High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.
Lynch C, Sakamuru S, Ooka M, Huang R, Klumpp-Thomas C, Shinn P, Gerhold D, Rossoshek A, Michael S, Casey W, Santillo MF, Fitzpatrick S, Thomas RS, Simeonov A, Xia M. Lynch C, et al. Among authors: ooka m. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:191-209. doi: 10.1146/annurev-pharmtox-112122-104310. Epub 2023 Jul 28. Annu Rev Pharmacol Toxicol. 2024. PMID: 37506331 Free PMC article. Review.
The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Solis O, Beccari AR, Iaconis D, Talarico C, Ruiz-Bedoya CA, Nwachukwu JC, Cimini A, Castelli V, Bertini R, Montopoli M, Cocetta V, Borocci S, Prandi IG, Flavahan K, Bahr M, Napiorkowski A, Chillemi G, Ooka M, Yang X, Zhang S, Xia M, Zheng W, Bonaventura J, Pomper MG, Hooper JE, Morales M, Rosenberg AZ, Nettles KW, Jain SK, Allegretti M, Michaelides M. Solis O, et al. Among authors: ooka m. Sci Adv. 2022 Dec 2;8(48):eadd4150. doi: 10.1126/sciadv.add4150. Epub 2022 Nov 30. Sci Adv. 2022. PMID: 36449624 Free PMC article.
The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Solis O, Beccari AR, Iaconis D, Talarico C, Ruiz-Bedoya CA, Nwachukwu JC, Cimini A, Castelli V, Bertini R, Montopoli M, Cocetta V, Borocci S, Prandi IG, Flavahan K, Bahr M, Napiorkowski A, Chillemi G, Ooka M, Yang X, Zhang S, Xia M, Zheng W, Bonaventura J, Pomper MG, Hooper JE, Morales M, Rosenberg AZ, Nettles KW, Jain SK, Allegretti M, Michaelides M. Solis O, et al. Among authors: ooka m. bioRxiv [Preprint]. 2022 May 23:2022.05.21.492920. doi: 10.1101/2022.05.21.492920. bioRxiv. 2022. PMID: 35665018 Free PMC article. Updated. Preprint.
XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA.
Hirota K, Ooka M, Shimizu N, Yamada K, Tsuda M, Ibrahim MA, Yamada S, Sasanuma H, Masutani M, Takeda S. Hirota K, et al. Among authors: ooka m. Genes Cells. 2022 May;27(5):331-344. doi: 10.1111/gtc.12929. Epub 2022 Mar 1. Genes Cells. 2022. PMID: 35194903 Free PMC article.
51 results