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RXR partial agonist produced by side chain repositioning of alkoxy RXR full agonist retains antitype 2 diabetes activity without the adverse effects.
Kawata K, Morishita K, Nakayama M, Yamada S, Kobayashi T, Furusawa Y, Arimoto-Kobayashi S, Oohashi T, Makishima M, Naitou H, Ishitsubo E, Tokiwa H, Tai A, Kakuta H. Kawata K, et al. Among authors: oohashi t. J Med Chem. 2015 Jan 22;58(2):912-26. doi: 10.1021/jm501863r. Epub 2014 Dec 17. J Med Chem. 2015. PMID: 25486327
RXR Partial Agonist CBt-PMN Exerts Therapeutic Effects on Type 2 Diabetes without the Side Effects of RXR Full Agonists.
Kakuta H, Yakushiji N, Shinozaki R, Ohsawa F, Yamada S, Ohta Y, Kawata K, Nakayama M, Hagaya M, Fujiwara C, Makishima M, Uno S, Tai A, Maehara A, Nakayama M, Oohashi T, Yasui H, Yoshikawa Y. Kakuta H, et al. Among authors: oohashi t. ACS Med Chem Lett. 2012 Apr 9;3(5):427-32. doi: 10.1021/ml300055n. eCollection 2012 May 10. ACS Med Chem Lett. 2012. PMID: 24900488 Free PMC article.
The 3'-untranslated region of ADAMTS1 regulates its mRNA stability.
Hatipoglu OF, Hirohata S, Yaykasli KO, Cilek MZ, Demircan K, Shinohata R, Yonezawa T, Oohashi T, Kusachi S, Ninomiya Y. Hatipoglu OF, et al. Among authors: oohashi t. Acta Med Okayama. 2009 Apr;63(2):79-85. doi: 10.18926/AMO/31831. Acta Med Okayama. 2009. PMID: 19404339 Free article.
Isolation and structure of the COL4A6 gene encoding the human alpha 6(IV) collagen chain and comparison with other type IV collagen genes.
Oohashi T, Ueki Y, Sugimoto M, Ninomiya Y. Oohashi T, et al. J Biol Chem. 1995 Nov 10;270(45):26863-7. doi: 10.1074/jbc.270.45.26863. J Biol Chem. 1995. PMID: 7592929 Free article.
The genes COL4A5 and COL4A6, coding for the basement membrane collagen chains, alpha 5(IV) and alpha 6(IV), respectively, are located head-to-head in close proximity on human chromosome Xq22, and COL4A6 is transcribed from two alternative promoters in a tissue-specific fashion (S …
The genes COL4A5 and COL4A6, coding for the basement membrane collagen chains, alpha 5(IV) and alpha 6(IV), respectively, are located head-t …
Host-produced ADAMTS4 Inhibits Early-Stage Tumor Growth.
Asano K, Edamatsu M, Hatipoglu OF, Inagaki J, Ono M, Ohtsuki T, Oohashi T, Hirohata S. Asano K, et al. Among authors: oohashi t. Acta Med Okayama. 2018 Jun;72(3):257-266. doi: 10.18926/AMO/56071. Acta Med Okayama. 2018. PMID: 29926003 Free article.
Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies.
Ninomiya Y, Kagawa M, Iyama K, Naito I, Kishiro Y, Seyer JM, Sugimoto M, Oohashi T, Sado Y. Ninomiya Y, et al. Among authors: oohashi t. J Cell Biol. 1995 Sep;130(5):1219-29. doi: 10.1083/jcb.130.5.1219. J Cell Biol. 1995. PMID: 7657706 Free PMC article.
In addition we reported a novel observation that the COL4A6 gene is transcribed from two alternative promoters in a tissue-specific manner (Sugimoto, M., T. Oohashi, and Y. Ninomiya. 1994. Proc. Natl. Acad. Sci. USA. 91:11679-11683). ...
In addition we reported a novel observation that the COL4A6 gene is transcribed from two alternative promoters in a tissue-specific manner ( …
148 results