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Platelet Acetyl-CoA Carboxylase Phosphorylation: A Risk Stratification Marker That Reveals Platelet-Lipid Interplay in Coronary Artery Disease Patients.
Kautbally S, Lepropre S, Onselaer MB, Le Rigoleur A, Ginion A, De Meester de Ravenstein C, Ambroise J, Boudjeltia KZ, Octave M, Wéra O, Hego A, Pincemail J, Cheramy-Bien JP, Huby T, Giera M, Gerber B, Pouleur AC, Guigas B, Vanoverschelde JL, Kefer J, Bertrand L, Oury C, Horman S, Beauloye C. Kautbally S, et al. Among authors: onselaer mb. JACC Basic Transl Sci. 2019 Sep 11;4(5):596-610. doi: 10.1016/j.jacbts.2019.04.005. eCollection 2019 Sep. JACC Basic Transl Sci. 2019. PMID: 31768476 Free PMC article.
AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.
Lepropre S, Kautbally S, Octave M, Ginion A, Onselaer MB, Steinberg GR, Kemp BE, Hego A, Wéra O, Brouns S, Swieringa F, Giera M, Darley-Usmar VM, Ambroise J, Guigas B, Heemskerk J, Bertrand L, Oury C, Beauloye C, Horman S. Lepropre S, et al. Among authors: onselaer mb. Blood. 2018 Sep 13;132(11):1180-1192. doi: 10.1182/blood-2018-02-831503. Epub 2018 Jul 17. Blood. 2018. PMID: 30018077 Free PMC article.
Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?
Slater A, Perrella G, Onselaer MB, Martin EM, Gauer JS, Xu RG, Heemskerk JW, Ariëns RAS, Watson SP. Slater A, et al. Among authors: onselaer mb. Platelets. 2019;30(3):281-289. doi: 10.1080/09537104.2018.1508649. Epub 2018 Aug 15. Platelets. 2019. PMID: 30110193
Comparison of the GPVI inhibitors losartan and honokiol.
Onselaer MB, Nagy M, Pallini C, Pike JA, Perrella G, Quintanilla LG, Eble JA, Poulter NS, Heemskerk JWM, Watson SP. Onselaer MB, et al. Platelets. 2020;31(2):187-197. doi: 10.1080/09537104.2019.1585526. Epub 2019 Mar 8. Platelets. 2020. PMID: 30849265 Free PMC article.
Fibrin and D-dimer bind to monomeric GPVI.
Onselaer MB, Hardy AT, Wilson C, Sanchez X, Babar AK, Miller JLC, Watson CN, Watson SK, Bonna A, Philippou H, Herr AB, Mezzano D, Ariëns RAS, Watson SP. Onselaer MB, et al. Blood Adv. 2017 Aug 15;1(19):1495-1504. doi: 10.1182/bloodadvances.2017007732. eCollection 2017 Aug 22. Blood Adv. 2017. PMID: 29296791 Free PMC article.
Immobilized fibrinogen activates human platelets through glycoprotein VI.
Mangin PH, Onselaer MB, Receveur N, Le Lay N, Hardy AT, Wilson C, Sanchez X, Loyau S, Dupuis A, Babar AK, Miller JL, Philippou H, Hughes CE, Herr AB, Ariëns RA, Mezzano D, Jandrot-Perrus M, Gachet C, Watson SP. Mangin PH, et al. Among authors: onselaer mb. Haematologica. 2018 May;103(5):898-907. doi: 10.3324/haematol.2017.182972. Epub 2018 Feb 22. Haematologica. 2018. PMID: 29472360 Free PMC article.
The Ca(2+) /calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets.
Onselaer MB, Oury C, Hunter RW, Eeckhoudt S, Barile N, Lecut C, Morel N, Viollet B, Jacquet LM, Bertrand L, Sakamoto K, Vanoverschelde JL, Beauloye C, Horman S. Onselaer MB, et al. J Thromb Haemost. 2014 Jun;12(6):973-86. doi: 10.1111/jth.12568. J Thromb Haemost. 2014. PMID: 24655923 Free article.