Ondeck C - Search Results

1

Symptomatic treatment of botulism with a clinically approved small molecule.

Vazquez-Cintron E, Machamer J, Ondeck C, Pagarigan K, Winner B, Bodner P, Kelly K, Pennington MR, McNutt P. Vazquez-Cintron E, et al. Among authors: ondeck c. JCI Insight. 2020 Jan 30;5(2):e132891. doi: 10.1172/jci.insight.132891. JCI Insight. 2020. PMID: 31996484 Free PMC article.

2

Corneal Endothelial Cell Toxicity Determines Long-Term Outcome After Ocular Exposure to Sulfur Mustard Vapor.

McNutt PM, Nguyen DL, Nelson MR, Lyman ME, Eisen MM, Ondeck CA, Wolfe SE, Pagarigan KT, Mangkhalakhili MC, Kniffin DM, Hamilton TA. McNutt PM, et al. Among authors: ondeck ca. Cornea. 2020 May;39(5):640-648. doi: 10.1097/ICO.0000000000002278. Cornea. 2020. PMID: 32044824

3

Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins.

Lam KH, Tremblay JM, Vazquez-Cintron E, Perry K, Ondeck C, Webb RP, McNutt PM, Shoemaker CB, Jin R. Lam KH, et al. Among authors: ondeck c. Cell Rep. 2020 Feb 25;30(8):2526-2539.e6. doi: 10.1016/j.celrep.2020.01.107. Cell Rep. 2020. PMID: 32101733 Free PMC article.

4

Characterization and treatment of spontaneous recurrent seizures following nerve agent-induced status epilepticus in mice.

McCarren HS, Eisen MR, Nguyen DL, Dubée PB, Ardinger CE, Dunn EN, Haines KM, Santoro AN, Bodner PM, Ondeck CA, Honnold CL, McDonough JH, Beske PH, McNutt PM. McCarren HS, et al. Epilepsy Res. 2020 May;162:106320. doi: 10.1016/j.eplepsyres.2020.106320. Epub 2020 Mar 10. Epilepsy Res. 2020. PMID: 32182542 Free PMC article.

5

Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function.

Tremblay JM, Vazquez-Cintron E, Lam KH, Mukherjee J, Bedenice D, Ondeck CA, Conroy MT, Bodt SML, Winner BM, Webb RP, Ichtchenko K, Jin R, McNutt PM, Shoemaker CB. Tremblay JM, et al. Toxins (Basel). 2020 Sep 24;12(10):611. doi: 10.3390/toxins12100611. Toxins (Basel). 2020. PMID: 32987745 Free PMC article.

6

Neuronal delivery of antibodies has therapeutic effects in animal models of botulism.

McNutt PM, Vazquez-Cintron EJ, Tenezaca L, Ondeck CA, Kelly KE, Mangkhalakhili M, Machamer JB, Angeles CA, Glotfelty EJ, Cika J, Benjumea CH, Whitfield JT, Band PA, Shoemaker CB, Ichtchenko K. McNutt PM, et al. Sci Transl Med. 2021 Jan 6;13(575):eabd7789. doi: 10.1126/scitranslmed.abd7789. Sci Transl Med. 2021. PMID: 33408188 Free PMC article.

7

Antidotal treatment of botulism in rats by continuous infusion with 3,4-diaminopyridine.

Machamer JB, Vazquez-Cintron EJ, O'Brien SW, Kelly KE, Altvater AC, Pagarigan KT, Dubee PB, Ondeck CA, McNutt PM. Machamer JB, et al. Among authors: ondeck ca. Mol Med. 2022 Jun 3;28(1):61. doi: 10.1186/s10020-022-00487-4. Mol Med. 2022. PMID: 35659174 Free PMC article.

8

Intramuscular delivery of formulated RNA encoding six linked nanobodies is highly protective for exposures to three Botulinum neurotoxin serotypes.

Mukherjee J, Ondeck CA, Tremblay JM, Archer J, Debatis M, Foss A, Awata J, Erasmus JH, McNutt PM, Shoemaker CB. Mukherjee J, et al. Among authors: ondeck ca. Sci Rep. 2022 Jul 8;12(1):11664. doi: 10.1038/s41598-022-15876-2. Sci Rep. 2022. PMID: 35803998 Free PMC article.

9

Neuromuscular recovery from botulism involves multiple forms of compensatory plasticity.

Machamer JB, Vazquez-Cintron EJ, Stenslik MJ, Pagarigan KT, Bradford AB, Ondeck CA, McNutt PM. Machamer JB, et al. Among authors: ondeck ca. Front Cell Neurosci. 2023 Aug 15;17:1226194. doi: 10.3389/fncel.2023.1226194. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37650071 Free PMC article.

10

Aminopyridines Restore Ventilation and Reverse Respiratory Acidosis at Late Stages of Botulism in Mice.

McClintic WT, Chandler ZD, Karchalla LM, Ondeck CA, O'Brien SW, Campbell CJ, Jacobson AR, McNutt PM. McClintic WT, et al. Among authors: ondeck ca. J Pharmacol Exp Ther. 2024 Jan 17;388(2):637-646. doi: 10.1124/jpet.123.001773. J Pharmacol Exp Ther. 2024. PMID: 37977816 Free PMC article.

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