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Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease.
Monteleone G, Neurath MF, Ardizzone S, Di Sabatino A, Fantini MC, Castiglione F, Scribano ML, Armuzzi A, Caprioli F, Sturniolo GC, Rogai F, Vecchi M, Atreya R, Bossa F, Onali S, Fichera M, Corazza GR, Biancone L, Savarino V, Pica R, Orlando A, Pallone F. Monteleone G, et al. Among authors: onali s. N Engl J Med. 2015 Mar 19;372(12):1104-13. doi: 10.1056/NEJMoa1407250. N Engl J Med. 2015. PMID: 25785968 Free article. Clinical Trial.
Comparative Efficacy of Vedolizumab and Adalimumab in Ulcerative Colitis Patients Previously Treated With Infliximab.
Favale A, Onali S, Caprioli F, Pugliese D, Armuzzi A, Macaluso FS, Orlando A, Viola A, Fries W, Rispo A, Castiglione F, Mocci G, Chicco F, Usai P, Calabrese E, Biancone L, Monteleone G, Fantini MC; Italian Group for the study of Inflammatory Bowel Disease (IG-IBD). Favale A, et al. Among authors: onali s. Inflamm Bowel Dis. 2019 Oct 18;25(11):1805-1812. doi: 10.1093/ibd/izz057. Inflamm Bowel Dis. 2019. PMID: 30931477
Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis.
Di Giovangiulio M, Rizzo A, Franzè E, Caprioli F, Facciotti F, Onali S, Favale A, Stolfi C, Fehling HJ, Monteleone G, Fantini MC. Di Giovangiulio M, et al. Among authors: onali s. Front Immunol. 2019 Sep 11;10:2158. doi: 10.3389/fimmu.2019.02158. eCollection 2019. Front Immunol. 2019. PMID: 31572375 Free PMC article.
Dual Targeted Therapy: a possible option for the management of refractory Inflammatory Bowel Disease.
Privitera G, Onali S, Pugliese D, Renna S, Savarino E, Viola A, Ribaldone DG, Buda A, Bezzio C, Fiorino G, Fantini MC, Scaldaferri F, Guidi L, Danese S, Gasbarrini A, Orlando A, Armuzzi A. Privitera G, et al. Among authors: onali s. J Crohns Colitis. 2020 Jul 17:jjaa149. doi: 10.1093/ecco-jcc/jjaa149. Online ahead of print. J Crohns Colitis. 2020. PMID: 32674156
A Pharmacological Batch of Mongersen that Downregulates Smad7 is Effective as Induction Therapy in Active Crohn's Disease: A Phase II, Open-Label Study.
Marafini I, Stolfi C, Troncone E, Lolli E, Onali S, Paoluzi OA, Fantini MC, Biancone L, Calabrese E, Di Grazia A, Monteleone I, Lenti MV, Di Sabatino A, Monteleone G. Marafini I, et al. Among authors: onali s. BioDrugs. 2021 May;35(3):325-336. doi: 10.1007/s40259-021-00482-x. Epub 2021 Apr 19. BioDrugs. 2021. PMID: 33871807 Free PMC article. Clinical Trial.
87 results