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NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding.
Levine DC, Kuo HY, Hong HK, Cedernaes J, Hepler C, Wright AG, Sommars MA, Kobayashi Y, Marcheva B, Gao P, Ilkayeva OR, Omura C, Ramsey KM, Newgard CB, Barish GD, Peek CB, Chandel NS, Mrksich M, Bass J. Levine DC, et al. Among authors: omura c. Nat Metab. 2021 Dec;3(12):1621-1632. doi: 10.1038/s42255-021-00498-1. Epub 2021 Dec 13. Nat Metab. 2021. PMID: 34903884 Free PMC article.
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, Wang X, Takahashi JS, Bass J. Marcheva B, et al. Among authors: omura c. Nature. 2010 Jul 29;466(7306):627-31. doi: 10.1038/nature09253. Nature. 2010. PMID: 20562852 Free PMC article.
Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice.
Shimomura K, Kumar V, Koike N, Kim TK, Chong J, Buhr ED, Whiteley AR, Low SS, Omura C, Fenner D, Owens JR, Richards M, Yoo SH, Hong HK, Vitaterna MH, Bass J, Pletcher MT, Wiltshire T, Hogenesch J, Lowrey PL, Takahashi JS. Shimomura K, et al. Among authors: omura c. Elife. 2013 Apr 9;2:e00426. doi: 10.7554/eLife.00426. Elife. 2013. PMID: 23580255 Free PMC article.
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.
Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C, Levine DC, Bacsik DJ, Gius D, Newgard CB, Goetzman E, Chandel NS, Denu JM, Mrksich M, Bass J. Peek CB, et al. Among authors: omura c. Science. 2013 Nov 1;342(6158):1243417. doi: 10.1126/science.1243417. Epub 2013 Sep 19. Science. 2013. PMID: 24051248 Free PMC article.
Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron.
Cedernaes J, Huang W, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XA, Takahashi JS, Mokadem M, Ahima RS, Bass J. Cedernaes J, et al. Among authors: omura c. Cell Metab. 2019 May 7;29(5):1078-1091.e5. doi: 10.1016/j.cmet.2019.01.023. Epub 2019 Feb 28. Cell Metab. 2019. PMID: 30827863 Free PMC article.
A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J. Marcheva B, et al. Among authors: omura c. Genes Dev. 2020 Aug 1;34(15-16):1089-1105. doi: 10.1101/gad.338178.120. Epub 2020 Jul 2. Genes Dev. 2020. PMID: 32616519 Free PMC article.
Erratum: A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Manning Fox JE, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J. Marcheva B, et al. Among authors: omura c. Genes Dev. 2021 Mar 1;35(5-6):425. doi: 10.1101/gad.348303.121. Genes Dev. 2021. PMID: 33649163 Free PMC article. No abstract available.
22 results