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cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization.
J Med Chem. 2006 Jun 1;49(11):3068-76. doi: 10.1021/jm0600085.
J Med Chem. 2006.
PMID: 16722626
(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.
Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, Liu S, McClure LD, McPherson RK, Olson TV, Orena SJ, Parker JC, Rocke BN, Soeller WC, Soglia CB, Treadway JL, Vanvolkenburg MA, Zhao Z, Cox ED.
Wright SW, et al. Among authors: olson tv.
Bioorg Med Chem Lett. 2007 Oct 15;17(20):5638-42. doi: 10.1016/j.bmcl.2007.07.081. Epub 2007 Aug 22.
Bioorg Med Chem Lett. 2007.
PMID: 17822893
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Discovery of triazolopyrimidine-based PDE8B inhibitors: exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetes.
DeNinno MP, Wright SW, Etienne JB, Olson TV, Rocke BN, Corbett JW, Kung DW, DiRico KJ, Andrews KM, Millham ML, Parker JC, Esler W, van Volkenburg M, Boyer DD, Houseknecht KL, Doran SD.
DeNinno MP, et al. Among authors: olson tv.
Bioorg Med Chem Lett. 2012 Sep 1;22(17):5721-6. doi: 10.1016/j.bmcl.2012.06.079. Epub 2012 Jul 6.
Bioorg Med Chem Lett. 2012.
PMID: 22858141
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1,5-Substituted nipecotic amides: selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability.
DeNinno MP, Wright SW, Visser MS, Etienne JB, Moore DE, Olson TV, Rocke BN, Andrews MP, Zarbo C, Millham ML, Boscoe BP, Boyer DD, Doran SD, Houseknecht KL.
DeNinno MP, et al. Among authors: olson tv.
Bioorg Med Chem Lett. 2011 May 15;21(10):3095-8. doi: 10.1016/j.bmcl.2011.03.022. Epub 2011 Mar 11.
Bioorg Med Chem Lett. 2011.
PMID: 21459572
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Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.
Rath VL, Ammirati M, Danley DE, Ekstrom JL, Gibbs EM, Hynes TR, Mathiowetz AM, McPherson RK, Olson TV, Treadway JL, Hoover DJ.
Rath VL, et al. Among authors: olson tv.
Chem Biol. 2000 Sep;7(9):677-82. doi: 10.1016/s1074-5521(00)00004-1.
Chem Biol. 2000.
PMID: 10980448
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Small Molecules Revealed in a Screen Targeting Epithelial Scattering Are Inhibitors of Microtubule Polymerization.
Hoj TH, Robinson RJ, Burton JC, Densley-Ure RA, Olson TV, Williams LK, Coward L, Gorman G, Hansen MD.
Hoj TH, et al. Among authors: olson tv.
J Biomol Screen. 2016 Aug;21(7):671-9. doi: 10.1177/1087057116651850. Epub 2016 May 31.
J Biomol Screen. 2016.
PMID: 27245142
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