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Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.
Kameneva P, Artemov AV, Kastriti ME, Faure L, Olsen TK, Otte J, Erickson A, Semsch B, Andersson ER, Ratz M, Frisén J, Tischler AS, de Krijger RR, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundström E, Mei S, Kogner P, Baryawno N, Kharchenko PV, Adameyko I. Kameneva P, et al. Among authors: olsen tk. Nat Genet. 2021 May;53(5):694-706. doi: 10.1038/s41588-021-00818-x. Epub 2021 Apr 8. Nat Genet. 2021. PMID: 33833454 Free PMC article.
Rho-associated kinase is a therapeutic target in neuroblastoma.
Dyberg C, Fransson S, Andonova T, Sveinbjörnsson B, Lännerholm-Palm J, Olsen TK, Forsberg D, Herlenius E, Martinsson T, Brodin B, Kogner P, Johnsen JI, Wickström M. Dyberg C, et al. Among authors: olsen tk. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6603-E6612. doi: 10.1073/pnas.1706011114. Epub 2017 Jul 24. Proc Natl Acad Sci U S A. 2017. PMID: 28739902 Free PMC article.
Introduction to Single-Cell RNA Sequencing.
Olsen TK, Baryawno N. Olsen TK, et al. Curr Protoc Mol Biol. 2018 Apr;122(1):e57. doi: 10.1002/cpmb.57. Curr Protoc Mol Biol. 2018. PMID: 29851283
Inhibition of Rho-Associated Kinase Suppresses Medulloblastoma Growth.
Dyberg C, Andonova T, Olsen TK, Brodin B, Kool M, Kogner P, Johnsen JI, Wickström M. Dyberg C, et al. Among authors: olsen tk. Cancers (Basel). 2019 Dec 26;12(1):73. doi: 10.3390/cancers12010073. Cancers (Basel). 2019. PMID: 31888022 Free PMC article.
Integrative discovery of treatments for high-risk neuroblastoma.
Almstedt E, Elgendy R, Hekmati N, Rosén E, Wärn C, Olsen TK, Dyberg C, Doroszko M, Larsson I, Sundström A, Arsenian Henriksson M, Påhlman S, Bexell D, Vanlandewijck M, Kogner P, Jörnsten R, Krona C, Nelander S. Almstedt E, et al. Among authors: olsen tk. Nat Commun. 2020 Jan 3;11(1):71. doi: 10.1038/s41467-019-13817-8. Nat Commun. 2020. PMID: 31900415 Free PMC article.
The immune cell atlas of human neuroblastoma.
Verhoeven BM, Mei S, Olsen TK, Gustafsson K, Valind A, Lindström A, Gisselsson D, Fard SS, Hagerling C, Kharchenko PV, Kogner P, Johnsen JI, Baryawno N. Verhoeven BM, et al. Among authors: olsen tk. Cell Rep Med. 2022 Jun 21;3(6):100657. doi: 10.1016/j.xcrm.2022.100657. Epub 2022 Jun 9. Cell Rep Med. 2022. PMID: 35688160 Free PMC article.
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma.
Olsen TK, Dyberg C, Embaie BT, Alchahin A, Milosevic J, Ding J, Otte J, Tümmler C, Hed Myrberg I, Westerhout EM, Koster J, Versteeg R, Ding HF, Kogner P, Johnsen JI, Sykes DB, Baryawno N. Olsen TK, et al. JCI Insight. 2022 Aug 9;7(17):e153836. doi: 10.1172/jci.insight.153836. JCI Insight. 2022. PMID: 35943801 Free PMC article.
Single-cell analyses of metastatic bone marrow in human neuroblastoma reveals microenvironmental remodeling and metastatic signature.
Mei S, Alchahin AM, Embaie BT, Gavriliuc IM, Verhoeven BM, Zhao T, Li X, Jeffries NE, Pepich A, Sarkar H, Olsen TK, Wickström M, Stenman J, Reina-Bedoya O, Kharchenko PV, Saylor PJ, Johnsen JI, Sykes DB, Kogner P, Baryawno N. Mei S, et al. Among authors: olsen tk. JCI Insight. 2024 Feb 15;9(6):e173337. doi: 10.1172/jci.insight.173337. JCI Insight. 2024. PMID: 38358826 Free PMC article.
28 results