Olsen SK - Search Results

1

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity.

Lv D, Pal P, Liu X, Jia Y, Thummuri D, Zhang P, Hu W, Pei J, Zhang Q, Zhou S, Khan S, Zhang X, Hua N, Yang Q, Arango S, Zhang W, Nayak D, Olsen SK, Weintraub ST, Hromas R, Konopleva M, Yuan Y, Zheng G, Zhou D. Lv D, et al. Among authors: olsen sk. Nat Commun. 2021 Nov 25;12(1):6896. doi: 10.1038/s41467-021-27210-x. Nat Commun. 2021. PMID: 34824248 Free PMC article.

2

Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI.

Yuan L, Lv Z, Atkison JH, Olsen SK. Yuan L, et al. Among authors: olsen sk. Nat Commun. 2017 Aug 8;8(1):211. doi: 10.1038/s41467-017-00272-6. Nat Commun. 2017. PMID: 28790309 Free PMC article.

3

Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34.

Williams KM, Qie S, Atkison JH, Salazar-Arango S, Alan Diehl J, Olsen SK. Williams KM, et al. Among authors: olsen sk. Nat Commun. 2019 Jul 24;10(1):3296. doi: 10.1038/s41467-019-11061-8. Nat Commun. 2019. PMID: 31341161 Free PMC article.

4

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.

Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK. Rut W, et al. Among authors: olsen sk. Sci Adv. 2020 Oct 16;6(42):eabd4596. doi: 10.1126/sciadv.abd4596. Print 2020 Oct. Sci Adv. 2020. PMID: 33067239 Free PMC article.

5

Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification.

Yuan L, Lv Z, Adams MJ, Olsen SK. Yuan L, et al. Among authors: olsen sk. Nat Commun. 2021 Apr 22;12(1):2370. doi: 10.1038/s41467-021-22598-y. Nat Commun. 2021. PMID: 33888705 Free PMC article.

6

PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.

Yin S, Liu L, Brobbey C, Palanisamy V, Ball LE, Olsen SK, Ostrowski MC, Gan W. Yin S, et al. Among authors: olsen sk. Nat Commun. 2021 Jun 8;12(1):3444. doi: 10.1038/s41467-021-23833-2. Nat Commun. 2021. PMID: 34103528 Free PMC article.

7

Clearing the air: Uniquely engaging furin as an approach to cystic fibrosis therapy.

Nayak D, Wasmuth EV, Olsen SK. Nayak D, et al. Among authors: olsen sk. Cell Chem Biol. 2022 Jun 16;29(6):927-929. doi: 10.1016/j.chembiol.2022.05.011. Cell Chem Biol. 2022. PMID: 35714591 Free PMC article.

8

Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6.

Yuan L, Gao F, Lv Z, Nayak D, Nayak A, Santos Bury PD, Cano KE, Jia L, Oleinik N, Atilgan FC, Ogretmen B, Williams KM, Davies C, El Oualid F, Wasmuth EV, Olsen SK. Yuan L, et al. Among authors: olsen sk. Nat Commun. 2022 Aug 19;13(1):4880. doi: 10.1038/s41467-022-32613-5. Nat Commun. 2022. PMID: 35986001 Free PMC article.

9

Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease.

Nayak D, Dos Santos Bury P, Drag M, Nijkerk AN, El Oualid F, Olsen SK. Nayak D, et al. Among authors: olsen sk. Methods Mol Biol. 2023;2591:171-188. doi: 10.1007/978-1-0716-2803-4_11. Methods Mol Biol. 2023. PMID: 36350549

10

Structural insights into BCDX2 complex function in homologous recombination.

Rawal Y, Jia L, Meir A, Zhou S, Kaur H, Ruben EA, Kwon Y, Bernstein KA, Jasin M, Taylor AB, Burma S, Hromas R, Mazin AV, Zhao W, Zhou D, Wasmuth EV, Greene EC, Sung P, Olsen SK. Rawal Y, et al. Among authors: olsen sk. Nature. 2023 Jul;619(7970):640-649. doi: 10.1038/s41586-023-06219-w. Epub 2023 Jun 21. Nature. 2023. PMID: 37344589

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