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Page 1
Extended interval dosing with ocrelizumab in multiple sclerosis.
Novak F, Bajwa HM, Østergaard K, Berg JM, Madsen JS, Olsen DA, Urbonaviciute I, Illes Z, Stilund ML, Romme Christensen J, Bramow S, Sellebjerg F, Sejbaek T. Novak F, et al. Among authors: olsen da. Mult Scler. 2024 Apr 22:13524585241245296. doi: 10.1177/13524585241245296. Online ahead of print. Mult Scler. 2024. PMID: 38646949
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development.
Wirjanata G, Lin J, Dziekan JM, El Sahili A, Chung Z, Tjia S, Binte Zulkifli NE, Boentoro J, Tham R, Jia LS, Go KD, Yu H, Partridge A, Olsen D, Prabhu N, Sobota RM, Nordlund P, Lescar J, Bozdech Z. Wirjanata G, et al. Among authors: olsen d. Cell Chem Biol. 2024 Apr 18;31(4):743-759.e8. doi: 10.1016/j.chembiol.2024.03.002. Epub 2024 Apr 8. Cell Chem Biol. 2024. PMID: 38593807
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities.
Boshoff HIM, Young K, Ahn YM, Yadav VD, Crowley BM, Yang L, Su J, Oh S, Arora K, Andrews J, Manikkam M, Sutphin M, Smith AJ, Weiner DM, Piazza MK, Fleegle JD, Gomez F, Dayao EK, Prideaux B, Zimmerman M, Kaya F, Sarathy J, Tan VY, Via LE, Tschirret-Guth R, Lenaerts AJ, Robertson GT, Dartois V, Olsen DB, Barry CE 3rd. Boshoff HIM, et al. Among authors: olsen db. ACS Infect Dis. 2024 Apr 6. doi: 10.1021/acsinfecdis.4c00025. Online ahead of print. ACS Infect Dis. 2024. PMID: 38581700
Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease.
Mudhasani RR, Golden JW, Adam GC, Hartingh TJ, Kota KP, Ordonez D, Quackenbush CR, Tran JP, Cline C, Williams JA, Zeng X, Olsen DB, Lieberman LA, Boyce C, Ginnetti A, Meinig JM, Panchal RG, Mucker EM. Mudhasani RR, et al. Among authors: olsen db. Microbiol Spectr. 2024 Apr 2;12(4):e0358623. doi: 10.1128/spectrum.03586-23. Epub 2024 Feb 23. Microbiol Spectr. 2024. PMID: 38391232 Free article.
Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.
Shurtleff VW, Layton ME, Parish CA, Perkins JJ, Schreier JD, Wang Y, Adam GC, Alvarez N, Bahmanjah S, Bahnck-Teets CM, Boyce CW, Burlein C, Cabalu TD, Campbell BT, Carroll SS, Chang W, de Lera Ruiz M, Dolgov E, Fay JF, Fox NG, Goh SL, Hartingh TJ, Hurzy DM, Kelly MJ 3rd, Klein DJ, Klingler FM, Krishnamurthy H, Kudalkar S, Mayhood TW, McKenna PM, Murray EM, Nahas D, Nawrat CC, Park S, Qian D, Roecker AJ, Sharma V, Shipe WD, Su J, Taggart RV, Truong Q, Wu Y, Zhou X, Zhuang N, Perlin DS, Olsen DB, Howe JA, McCauley JA. Shurtleff VW, et al. Among authors: olsen db. J Med Chem. 2024 Mar 14;67(5):3935-3958. doi: 10.1021/acs.jmedchem.3c02248. Epub 2024 Feb 16. J Med Chem. 2024. PMID: 38365209
990 results