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TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.
Olschewski A, Veale EL, Nagy BM, Nagaraj C, Kwapiszewska G, Antigny F, Lambert M, Humbert M, Czirják G, Enyedi P, Mathie A. Olschewski A, et al. Eur Respir J. 2017 Nov 9;50(5):1700754. doi: 10.1183/13993003.00754-2017. Print 2017 Nov. Eur Respir J. 2017. PMID: 29122916 Free article. Review.
Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation.
Erfinanda L, Zou L, Gutbier B, Kneller L, Weidenfeld S, Michalick L, Lei D, Reppe K, Teixeira Alves LG, Schneider B, Zhang Q, Li C, Fatykhova D, Schneider P, Liedtke W, Sohara E, Mitchell TJ, Gruber AD, Hocke A, Hippenstiel S, Suttorp N, Olschewski A, Mall MA, Witzenrath M, Kuebler WM. Erfinanda L, et al. Among authors: olschewski a. Sci Transl Med. 2022 Dec 7;14(674):eabg8577. doi: 10.1126/scitranslmed.abg8577. Epub 2022 Dec 7. Sci Transl Med. 2022. PMID: 36475904
Impact of TASK-1 in human pulmonary artery smooth muscle cells.
Olschewski A, Li Y, Tang B, Hanze J, Eul B, Bohle RM, Wilhelm J, Morty RE, Brau ME, Weir EK, Kwapiszewska G, Klepetko W, Seeger W, Olschewski H. Olschewski A, et al. Among authors: olschewski h. Circ Res. 2006 Apr 28;98(8):1072-80. doi: 10.1161/01.RES.0000219677.12988.e9. Epub 2006 Mar 30. Circ Res. 2006. PMID: 16574908
Origin of neomuscularized vessels in mice exposed to chronic hypoxia.
Crnkovic S, Hrzenjak A, Marsh LM, Olschewski A, Kwapiszewska G. Crnkovic S, et al. Among authors: olschewski a. Respir Physiol Neurobiol. 2011 Dec 15;179(2-3):342-5. doi: 10.1016/j.resp.2011.09.016. Epub 2011 Oct 1. Respir Physiol Neurobiol. 2011. PMID: 22000991
Peroxisome proliferator-activated receptor-β/δ, the acute signaling factor in prostacyclin-induced pulmonary vasodilation.
Li Y, Connolly M, Nagaraj C, Tang B, Bálint Z, Popper H, Smolle-Juettner FM, Lindenmann J, Kwapiszewska G, Aaronson PI, Wohlkoenig C, Leithner K, Olschewski H, Olschewski A. Li Y, et al. Among authors: olschewski h, olschewski a. Am J Respir Cell Mol Biol. 2012 Mar;46(3):372-9. doi: 10.1165/rcmb.2010-0428OC. Epub 2011 Oct 20. Am J Respir Cell Mol Biol. 2012. PMID: 22021335
PAR-2 inhibition reverses experimental pulmonary hypertension.
Kwapiszewska G, Markart P, Dahal BK, Kojonazarov B, Marsh LM, Schermuly RT, Taube C, Meinhardt A, Ghofrani HA, Steinhoff M, Seeger W, Preissner KT, Olschewski A, Weissmann N, Wygrecka M. Kwapiszewska G, et al. Among authors: olschewski a. Circ Res. 2012 Apr 27;110(9):1179-91. doi: 10.1161/CIRCRESAHA.111.257568. Epub 2012 Mar 29. Circ Res. 2012. PMID: 22461388
Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries.
Nagaraj C, Tang B, Bálint Z, Wygrecka M, Hrzenjak A, Kwapiszewska G, Stacher E, Lindenmann J, Weir EK, Olschewski H, Olschewski A. Nagaraj C, et al. Among authors: olschewski h, olschewski a. Eur Respir J. 2013 Jan;41(1):85-95. doi: 10.1183/09031936.00211811. Epub 2012 Apr 20. Eur Respir J. 2013. PMID: 22523355 Free article.
Angiostatic factors in the pulmonary endarterectomy material from chronic thromboembolic pulmonary hypertension patients cause endothelial dysfunction.
Zabini D, Nagaraj C, Stacher E, Lang IM, Nierlich P, Klepetko W, Heinemann A, Olschewski H, Bálint Z, Olschewski A. Zabini D, et al. Among authors: olschewski h, olschewski a. PLoS One. 2012;7(8):e43793. doi: 10.1371/journal.pone.0043793. Epub 2012 Aug 20. PLoS One. 2012. PMID: 22916307 Free PMC article.
159 results