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A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis.
Lluch A, Veiga SR, Latorre J, Moreno-Navarrete JM, Bonifaci N, Dien Nguyen V, Zhou Y, Höring M, Liebisch G, Olkkonen VM, Llobet-Navas D, Thomas G, Rodríguez-Barrueco R, Fernández-Real JM, Kozma SC, Ortega FJ. Lluch A, et al. Among authors: olkkonen vm. JCI Insight. 2022 Jul 22;7(14):e150461. doi: 10.1172/jci.insight.150461. JCI Insight. 2022. PMID: 35737463 Free PMC article.
PNPLA3 mediates hepatocyte triacylglycerol remodeling.
Ruhanen H, Perttilä J, Hölttä-Vuori M, Zhou Y, Yki-Järvinen H, Ikonen E, Käkelä R, Olkkonen VM. Ruhanen H, et al. Among authors: olkkonen vm. J Lipid Res. 2014 Apr;55(4):739-46. doi: 10.1194/jlr.M046607. Epub 2014 Feb 7. J Lipid Res. 2014. PMID: 24511104 Free PMC article.
MicroRNA-221-3p Regulates Angiopoietin-Like 8 (ANGPTL8) Expression in Adipocytes.
Mysore R, Ortega FJ, Latorre J, Ahonen M, Savolainen-Peltonen H, Fischer-Posovszky P, Wabitsch M, Olkkonen VM, Fernández-Real JM, Haridas PAN. Mysore R, et al. Among authors: olkkonen vm. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4001-4012. doi: 10.1210/jc.2017-00453. J Clin Endocrinol Metab. 2017. PMID: 28938482
OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism.
Kentala H, Koponen A, Vihinen H, Pirhonen J, Liebisch G, Pataj Z, Kivelä A, Li S, Karhinen L, Jääskeläinen E, Andrews R, Meriläinen L, Matysik S, Ikonen E, Zhou Y, Jokitalo E, Olkkonen VM. Kentala H, et al. Among authors: olkkonen vm. Cell Mol Life Sci. 2018 Nov;75(21):4041-4057. doi: 10.1007/s00018-018-2850-8. Epub 2018 Jun 12. Cell Mol Life Sci. 2018. PMID: 29947926
221 results