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A Recombinant Chimeric Protein-Based Vaccine Containing T-Cell Epitopes from Amastigote Proteins and Combined with Distinct Adjuvants, Induces Immunogenicity and Protection against Leishmania infantum Infection.
Lage DP, Vale DL, Linhares FP, Freitas CS, Machado AS, Cardoso JMO, de Oliveira D, Galvani NC, de Oliveira MP, Oliveira-da-Silva JA, Ramos FF, Tavares GSV, Ludolf F, Bandeira RS, Pereira IAG, Chávez-Fumagalli MA, Roatt BM, Machado-de-Ávila RA, Christodoulides M, Coelho EAF, Martins VT. Lage DP, et al. Among authors: oliveira da silva ja. Vaccines (Basel). 2022 Jul 19;10(7):1146. doi: 10.3390/vaccines10071146. Vaccines (Basel). 2022. PMID: 35891310 Free PMC article.
Leishmania infantum amastin protein incorporated in distinct adjuvant systems induces protection against visceral leishmaniasis.
Ribeiro PAF, Vale DL, Dias DS, Lage DP, Mendonça DVC, Ramos FF, Carvalho LM, Carvalho AMRS, Steiner BT, Roque MC, Oliveira-da-Silva JA, Oliveira JS, Tavares GSV, Galvani NC, Martins VT, Chávez-Fumagalli MA, Roatt BM, Moreira RLF, Menezes-Souza D, Oliveira MC, Machado-de-Ávila RA, Teixeira AL, Coelho EAF. Ribeiro PAF, et al. Cytokine. 2020 May;129:155031. doi: 10.1016/j.cyto.2020.155031. Epub 2020 Feb 12. Cytokine. 2020. PMID: 32062145
Liposomal Formulation of ChimeraT, a Multiple T-Cell Epitope-Containing Recombinant Protein, Is a Candidate Vaccine for Human Visceral Leishmaniasis.
Lage DP, Ribeiro PAF, Dias DS, Mendonça DVC, Ramos FF, Carvalho LM, Steiner BT, Tavares GSV, Martins VT, Machado AS, Oliveira-da-Silva JA, Santos TTO, Freitas CS, Oliveira JS, Roatt BM, Machado-de-Ávila RA, Humbert MV, Christodoulides M, Coelho EAF. Lage DP, et al. Vaccines (Basel). 2020 Jun 9;8(2):289. doi: 10.3390/vaccines8020289. Vaccines (Basel). 2020. PMID: 32526867 Free PMC article.
Evaluation of the protective efficacy of a Leishmania protein associated with distinct adjuvants against visceral leishmaniasis and in vitro immunogenicity in human cells.
Ribeiro PAF, Dias DS, Lage DP, Mendonça DVC, Vale DL, Ramos FF, Carvalho LM, Carvalho AMRS, Steiner BT, Roque MC, Oliveira-da-Silva JA, Oliveira JS, Tavares GSV, Martins VT, Chávez-Fumagalli MA, Roatt BM, Moreira RLF, Menezes-Souza D, Duarte MC, Oliveira MC, Machado-de-Ávila RA, Teixeira AL, Coelho EAF. Ribeiro PAF, et al. Parasitol Res. 2020 Aug;119(8):2609-2622. doi: 10.1007/s00436-020-06752-x. Epub 2020 Jun 13. Parasitol Res. 2020. PMID: 32535734
Leishmania infantum pyridoxal kinase evaluated in a recombinant protein and DNA vaccine to protects against visceral leishmaniasis.
Oliveira-da-Silva JA, Lage DP, Ramos FF, Machado AS, Tavares GSV, Mendonça DVC, Pereira IAG, Martins VT, Carvalho LM, Ludolf F, Santos TTO, Reis TAR, Oliveira CS, Bandeira RS, Silva AM, Costa LE, Oliveira JS, Duarte MC, Menezes-Souza D, Roatt BM, Teixeira AL, Coelho EAF. Oliveira-da-Silva JA, et al. Mol Immunol. 2020 Aug;124:161-171. doi: 10.1016/j.molimm.2020.06.010. Epub 2020 Jun 22. Mol Immunol. 2020. PMID: 32585510
A candidate vaccine for human visceral leishmaniasis based on a specific T cell epitope-containing chimeric protein protects mice against Leishmania infantum infection.
Lage DP, Ribeiro PAF, Dias DS, Mendonça DVC, Ramos FF, Carvalho LM, de Oliveira D, Steiner BT, Martins VT, Perin L, Machado AS, Santos TTO, Tavares GSV, Oliveira-da-Silva JA, Oliveira JS, Roatt BM, Machado-de-Ávila RA, Teixeira AL, Humbert MV, Coelho EAF, Christodoulides M. Lage DP, et al. NPJ Vaccines. 2020 Aug 13;5:75. doi: 10.1038/s41541-020-00224-0. eCollection 2020. NPJ Vaccines. 2020. PMID: 32821440 Free PMC article.
A Leishmania amastigote-specific hypothetical protein evaluated as recombinant protein plus Th1 adjuvant or DNA plasmid-based vaccine to protect against visceral leishmaniasis.
Oliveira-da-Silva JA, Machado AS, Ramos FF, Tavares GSV, Lage DP, Mendonça DVC, Pereira IAG, Santos TTO, Martins VT, Carvalho LM, Freitas CS, Ludolf F, Reis TAR, Bandeira RS, Silva AM, Costa LE, Oliveira JS, Duarte MC, Roatt BM, Teixeira AL, Coelho EAF. Oliveira-da-Silva JA, et al. Cell Immunol. 2020 Oct;356:104194. doi: 10.1016/j.cellimm.2020.104194. Epub 2020 Aug 13. Cell Immunol. 2020. PMID: 32827943
Leishmania eukaryotic elongation Factor-1 beta protein is immunogenic and induces parasitological protection in mice against Leishmania infantum infection.
Santos TTO, Machado AS, Ramos FF, Oliveira-da-Silva JA, Lage DP, Tavares GSV, Mendonça DVC, Cardoso MS, Siqueira WF, Martins VT, Ludolf F, Reis TAR, Carvalho LM, Freitas CS, Bandeira RS, Silva AM, Oliveira JS, Moreira RLF, Fujiwara RT, Roatt BM, Chávez-Fumagalli MA, Humbert MV, Teixeira AL, Coelho EAF. Santos TTO, et al. Microb Pathog. 2021 Feb;151:104745. doi: 10.1016/j.micpath.2021.104745. Epub 2021 Jan 21. Microb Pathog. 2021. PMID: 33485994
[No title available]
[No authors listed] [No authors listed] PMID: 33574303
Serodiagnosis of canine leishmaniasis using a novel recombinant chimeric protein constructed with distinct B-cell epitopes from antigenic Leishmania infantum proteins.
Vale DL, Lage DP, Machado AS, Freitas CS, de Oliveira D, Galvani NC, Fernandes BB, Luiz GP, Oliveira JS, Oliveira-da-Silva JA, Ramos FF, Santos TTO, Siqueira WF, Alves LA, Chávez-Fumagalli MA, de Magalhães-Soares DF, Silveira JAG, Bueno LL, Fujiwara RT, Machado-de-Ávila RA, Martins VT, Coelho EAF. Vale DL, et al. Vet Parasitol. 2021 Aug;296:109513. doi: 10.1016/j.vetpar.2021.109513. Epub 2021 Jul 1. Vet Parasitol. 2021. PMID: 34225189
41 results