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A recombinant Leishmania amastigote-specific protein, rLiHyG, with adjuvants, protects against infection with Leishmania infantum.
Machado AS, Lage DP, Vale DL, Freitas CS, Linhares FP, Cardoso JMO, Pereira IAG, Ramos FF, Tavares GSV, Ludolf F, Oliveira-da-Silva JA, Bandeira RS, Simões AC, Duarte MC, Oliveira JS, Christodoulides M, Chávez-Fumagalli MA, Roatt BM, Martins VT, Coelho EAF. Machado AS, et al. Acta Trop. 2022 Jun;230:106412. doi: 10.1016/j.actatropica.2022.106412. Epub 2022 Mar 16. Acta Trop. 2022. PMID: 35305943
Recombinant Leishmania eukaryotic elongation factor-1 beta protein: A potential diagnostic antigen to detect tegumentary and visceral leishmaniasis in dogs and humans.
Santos TTO, Cardoso MS, Machado AS, Siqueira WF, Ramos FF, Oliveira-da-Silva JA, Tavares GSV, Lage DP, Costa LE, de Freitas CS, Martins VT, Bandeira RS, Chávez-Fumagalli MA, Lyon S, Moreira RLF, de Magalhães-Soares DF, Silveira JAG, Tupinambás U, Caligiorne RB, Chaves AT, Rocha MOC, Fujiwara RT, Coelho EAF. Santos TTO, et al. Microb Pathog. 2019 Dec;137:103783. doi: 10.1016/j.micpath.2019.103783. Epub 2019 Oct 7. Microb Pathog. 2019. PMID: 31600536
A Leishmania infantum hypothetical protein evaluated as a recombinant protein and specific B-cell epitope for the serodiagnosis and prognosis of visceral leishmaniasis.
Machado AS, Ramos FF, Oliveira-da-Silva JA, Santos TTO, Ludolf F, Tavares GSV, Costa LE, Lage DP, Steiner BT, Chaves AT, Chávez-Fumagalli MA, de Magalhães-Soares DF, Silveira JAG, Napoles KMN, Tupinambás U, Duarte MC, Machado-de-Ávila RA, Bueno LL, Fujiwara RT, Moreira RLF, Rocha MOC, Caligiorne RB, Coelho EAF. Machado AS, et al. Acta Trop. 2020 Mar;203:105318. doi: 10.1016/j.actatropica.2019.105318. Epub 2019 Dec 20. Acta Trop. 2020. PMID: 31870709
Evaluation of Leishmania infantum pyridoxal kinase protein for the diagnosis of human and canine visceral leishmaniasis.
Oliveira-da-Silva JA, Machado AS, Ramos FF, Tavares GSV, Lage DP, Ludolf F, Steiner BT, Reis TAR, Santos TTO, Costa LE, Martins VT, Galvani NC, Chaves AT, Oliveira JS, Chávez-Fumagalli MA, de Magalhães-Soares DF, Duarte MC, Menezes-Souza D, Silveira JAG, Moreira RLF, Machado-de-Ávila RA, Tupinambás U, Gonçalves DU, Coelho EAF. Oliveira-da-Silva JA, et al. Immunol Lett. 2020 Apr;220:11-20. doi: 10.1016/j.imlet.2020.01.005. Epub 2020 Jan 22. Immunol Lett. 2020. PMID: 31981576
Leishmania infantum amastin protein incorporated in distinct adjuvant systems induces protection against visceral leishmaniasis.
Ribeiro PAF, Vale DL, Dias DS, Lage DP, Mendonça DVC, Ramos FF, Carvalho LM, Carvalho AMRS, Steiner BT, Roque MC, Oliveira-da-Silva JA, Oliveira JS, Tavares GSV, Galvani NC, Martins VT, Chávez-Fumagalli MA, Roatt BM, Moreira RLF, Menezes-Souza D, Oliveira MC, Machado-de-Ávila RA, Teixeira AL, Coelho EAF. Ribeiro PAF, et al. Cytokine. 2020 May;129:155031. doi: 10.1016/j.cyto.2020.155031. Epub 2020 Feb 12. Cytokine. 2020. PMID: 32062145
An immunoproteomics approach to identify Leishmania infantum proteins to be applied for the diagnosis of visceral leishmaniasis and human immunodeficiency virus co-infection.
Machado AS, Ramos FF, Oliveira-da-Silva JA, Santos TTO, Tavares GSV, Costa LE, Lage DP, Teixeira-Ferreira A, Perales J, Fernandes AP, Moreira RLF, Duarte MC, Tupinambás U, Caligiorne RB, Cota GF, Coelho EAF, Ludolf F. Machado AS, et al. Parasitology. 2020 Aug;147(9):932-939. doi: 10.1017/S0031182020000578. Epub 2020 Apr 20. Parasitology. 2020. PMID: 32308186 Free PMC article.
A clioquinol-containing Pluronic® F127 polymeric micelle system is effective in the treatment of visceral leishmaniasis in a murine model.
Tavares GSV, Mendonça DVC, Pereira IAG, Oliveira-da-Silva JA, Ramos FF, Lage DP, Machado AS, Carvalho LM, Reis TAR, Perin L, Carvalho AMRS, Ottoni FM, Ludolf F, Freitas CS, Bandeira RS, Silva AM, Chávez-Fumagalli MA, Duarte MC, Menezes-Souza D, Alves RJ, Roatt BM, Coelho EAF. Tavares GSV, et al. Parasite. 2020;27:29. doi: 10.1051/parasite/2020027. Epub 2020 Apr 30. Parasite. 2020. PMID: 32351209 Free PMC article.
Biotechnological applications from a Leishmania amastigote-specific hypothetical protein in the canine and human visceral leishmaniasis.
Oliveira-da-Silva JA, Machado AS, Tavares GSV, Ramos FF, Lage DP, Ludolf F, Steiner BT, Reis TAR, Santos TTO, Costa LE, Bandeira RS, Martins VT, Galvani NC, Chaves AT, Oliveira JS, Chávez-Fumagalli MA, Tupinambás U, de Magalhães-Soares DF, Silveira JAG, Lyon S, Machado-de-Ávila RA, Coelho EAF. Oliveira-da-Silva JA, et al. Microb Pathog. 2020 Oct;147:104283. doi: 10.1016/j.micpath.2020.104283. Epub 2020 May 30. Microb Pathog. 2020. PMID: 32485231
Evaluation of the protective efficacy of a Leishmania protein associated with distinct adjuvants against visceral leishmaniasis and in vitro immunogenicity in human cells.
Ribeiro PAF, Dias DS, Lage DP, Mendonça DVC, Vale DL, Ramos FF, Carvalho LM, Carvalho AMRS, Steiner BT, Roque MC, Oliveira-da-Silva JA, Oliveira JS, Tavares GSV, Martins VT, Chávez-Fumagalli MA, Roatt BM, Moreira RLF, Menezes-Souza D, Duarte MC, Oliveira MC, Machado-de-Ávila RA, Teixeira AL, Coelho EAF. Ribeiro PAF, et al. Parasitol Res. 2020 Aug;119(8):2609-2622. doi: 10.1007/s00436-020-06752-x. Epub 2020 Jun 13. Parasitol Res. 2020. PMID: 32535734
Leishmania infantum pyridoxal kinase evaluated in a recombinant protein and DNA vaccine to protects against visceral leishmaniasis.
Oliveira-da-Silva JA, Lage DP, Ramos FF, Machado AS, Tavares GSV, Mendonça DVC, Pereira IAG, Martins VT, Carvalho LM, Ludolf F, Santos TTO, Reis TAR, Oliveira CS, Bandeira RS, Silva AM, Costa LE, Oliveira JS, Duarte MC, Menezes-Souza D, Roatt BM, Teixeira AL, Coelho EAF. Oliveira-da-Silva JA, et al. Mol Immunol. 2020 Aug;124:161-171. doi: 10.1016/j.molimm.2020.06.010. Epub 2020 Jun 22. Mol Immunol. 2020. PMID: 32585510
41 results