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Biotechnological applications from a Leishmania amastigote-specific hypothetical protein in the canine and human visceral leishmaniasis.
Oliveira-da-Silva JA, Machado AS, Tavares GSV, Ramos FF, Lage DP, Ludolf F, Steiner BT, Reis TAR, Santos TTO, Costa LE, Bandeira RS, Martins VT, Galvani NC, Chaves AT, Oliveira JS, Chávez-Fumagalli MA, Tupinambás U, de Magalhães-Soares DF, Silveira JAG, Lyon S, Machado-de-Ávila RA, Coelho EAF. Oliveira-da-Silva JA, et al. Microb Pathog. 2020 Oct;147:104283. doi: 10.1016/j.micpath.2020.104283. Epub 2020 May 30. Microb Pathog. 2020. PMID: 32485231
A chloroquinoline derivate presents effective in vitro and in vivo antileishmanial activity against Leishmania species that cause tegumentary and visceral leishmaniasis.
Sousa JKT, Antinarelli LMR, Mendonça DVC, Lage DP, Tavares GSV, Dias DS, Ribeiro PAF, Ludolf F, Coelho VTS, Oliveira-da-Silva JA, Perin L, Oliveira BA, Alvarenga DF, Chávez-Fumagalli MA, Brandão GC, Nobre V, Pereira GR, Coimbra ES, Coelho EAF. Sousa JKT, et al. Parasitol Int. 2019 Dec;73:101966. doi: 10.1016/j.parint.2019.101966. Epub 2019 Jul 27. Parasitol Int. 2019. PMID: 31362122
Diagnostic markers selected by immunoproteomics and phage display applied for the serodiagnosis of canine leishmaniosis.
Machado JM, Costa LE, Dias DS, Ribeiro PAF, Martins VT, Lage DP, Carvalho GB, Franklin ML, Tavares GSV, Oliveira-da-Silva JA, Machado AS, Ramos LS, Nogueira LM, Mariano RMS, Moura HB, Silva ES, Teixeira-Neto RG, Campos-da-Paz M, Galdino AS, Coelho EAF. Machado JM, et al. Res Vet Sci. 2019 Oct;126:4-8. doi: 10.1016/j.rvsc.2019.08.010. Epub 2019 Aug 8. Res Vet Sci. 2019. PMID: 31415928 Review.
Recombinant Leishmania eukaryotic elongation factor-1 beta protein: A potential diagnostic antigen to detect tegumentary and visceral leishmaniasis in dogs and humans.
Santos TTO, Cardoso MS, Machado AS, Siqueira WF, Ramos FF, Oliveira-da-Silva JA, Tavares GSV, Lage DP, Costa LE, de Freitas CS, Martins VT, Bandeira RS, Chávez-Fumagalli MA, Lyon S, Moreira RLF, de Magalhães-Soares DF, Silveira JAG, Tupinambás U, Caligiorne RB, Chaves AT, Rocha MOC, Fujiwara RT, Coelho EAF. Santos TTO, et al. Microb Pathog. 2019 Dec;137:103783. doi: 10.1016/j.micpath.2019.103783. Epub 2019 Oct 7. Microb Pathog. 2019. PMID: 31600536
A Leishmania infantum hypothetical protein evaluated as a recombinant protein and specific B-cell epitope for the serodiagnosis and prognosis of visceral leishmaniasis.
Machado AS, Ramos FF, Oliveira-da-Silva JA, Santos TTO, Ludolf F, Tavares GSV, Costa LE, Lage DP, Steiner BT, Chaves AT, Chávez-Fumagalli MA, de Magalhães-Soares DF, Silveira JAG, Napoles KMN, Tupinambás U, Duarte MC, Machado-de-Ávila RA, Bueno LL, Fujiwara RT, Moreira RLF, Rocha MOC, Caligiorne RB, Coelho EAF. Machado AS, et al. Acta Trop. 2020 Mar;203:105318. doi: 10.1016/j.actatropica.2019.105318. Epub 2019 Dec 20. Acta Trop. 2020. PMID: 31870709
Evaluation of Leishmania infantum pyridoxal kinase protein for the diagnosis of human and canine visceral leishmaniasis.
Oliveira-da-Silva JA, Machado AS, Ramos FF, Tavares GSV, Lage DP, Ludolf F, Steiner BT, Reis TAR, Santos TTO, Costa LE, Martins VT, Galvani NC, Chaves AT, Oliveira JS, Chávez-Fumagalli MA, de Magalhães-Soares DF, Duarte MC, Menezes-Souza D, Silveira JAG, Moreira RLF, Machado-de-Ávila RA, Tupinambás U, Gonçalves DU, Coelho EAF. Oliveira-da-Silva JA, et al. Immunol Lett. 2020 Apr;220:11-20. doi: 10.1016/j.imlet.2020.01.005. Epub 2020 Jan 22. Immunol Lett. 2020. PMID: 31981576
Leishmania infantum amastin protein incorporated in distinct adjuvant systems induces protection against visceral leishmaniasis.
Ribeiro PAF, Vale DL, Dias DS, Lage DP, Mendonça DVC, Ramos FF, Carvalho LM, Carvalho AMRS, Steiner BT, Roque MC, Oliveira-da-Silva JA, Oliveira JS, Tavares GSV, Galvani NC, Martins VT, Chávez-Fumagalli MA, Roatt BM, Moreira RLF, Menezes-Souza D, Oliveira MC, Machado-de-Ávila RA, Teixeira AL, Coelho EAF. Ribeiro PAF, et al. Cytokine. 2020 May;129:155031. doi: 10.1016/j.cyto.2020.155031. Epub 2020 Feb 12. Cytokine. 2020. PMID: 32062145
An immunoproteomics approach to identify Leishmania infantum proteins to be applied for the diagnosis of visceral leishmaniasis and human immunodeficiency virus co-infection.
Machado AS, Ramos FF, Oliveira-da-Silva JA, Santos TTO, Tavares GSV, Costa LE, Lage DP, Teixeira-Ferreira A, Perales J, Fernandes AP, Moreira RLF, Duarte MC, Tupinambás U, Caligiorne RB, Cota GF, Coelho EAF, Ludolf F. Machado AS, et al. Parasitology. 2020 Aug;147(9):932-939. doi: 10.1017/S0031182020000578. Epub 2020 Apr 20. Parasitology. 2020. PMID: 32308186 Free PMC article.
A clioquinol-containing Pluronic® F127 polymeric micelle system is effective in the treatment of visceral leishmaniasis in a murine model.
Tavares GSV, Mendonça DVC, Pereira IAG, Oliveira-da-Silva JA, Ramos FF, Lage DP, Machado AS, Carvalho LM, Reis TAR, Perin L, Carvalho AMRS, Ottoni FM, Ludolf F, Freitas CS, Bandeira RS, Silva AM, Chávez-Fumagalli MA, Duarte MC, Menezes-Souza D, Alves RJ, Roatt BM, Coelho EAF. Tavares GSV, et al. Parasite. 2020;27:29. doi: 10.1051/parasite/2020027. Epub 2020 Apr 30. Parasite. 2020. PMID: 32351209 Free PMC article.
Liposomal Formulation of ChimeraT, a Multiple T-Cell Epitope-Containing Recombinant Protein, Is a Candidate Vaccine for Human Visceral Leishmaniasis.
Lage DP, Ribeiro PAF, Dias DS, Mendonça DVC, Ramos FF, Carvalho LM, Steiner BT, Tavares GSV, Martins VT, Machado AS, Oliveira-da-Silva JA, Santos TTO, Freitas CS, Oliveira JS, Roatt BM, Machado-de-Ávila RA, Humbert MV, Christodoulides M, Coelho EAF. Lage DP, et al. Vaccines (Basel). 2020 Jun 9;8(2):289. doi: 10.3390/vaccines8020289. Vaccines (Basel). 2020. PMID: 32526867 Free PMC article.
41 results