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HIV gp120 H375 is unique to HIV-1 subtype CRF01_AE and confers strong resistance to the entry inhibitor BMS-599793, a candidate microbicide drug.
Schader SM, Colby-Germinario SP, Quashie PK, Oliveira M, Ibanescu RI, Moisi D, Mespléde T, Wainberg MA. Schader SM, et al. Among authors: oliveira m. Antimicrob Agents Chemother. 2012 Aug;56(8):4257-67. doi: 10.1128/AAC.00639-12. Epub 2012 May 21. Antimicrob Agents Chemother. 2012. PMID: 22615295 Free PMC article.
HIV-1 group O integrase displays lower enzymatic efficiency and higher susceptibility to raltegravir than HIV-1 group M subtype B integrase.
Depatureaux A, Quashie PK, Mesplède T, Han Y, Koubi H, Plantier JC, Oliveira M, Moisi D, Brenner B, Wainberg MA. Depatureaux A, et al. Among authors: oliveira m. Antimicrob Agents Chemother. 2014 Dec;58(12):7141-50. doi: 10.1128/AAC.03819-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25224008 Free PMC article.
9,522 results