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New synthetic molecules incorporated into polymeric micelles used for treatment against visceral leishmaniasis.
Freitas CS, Pereira IAG, Lage DP, Vale DL, Pimenta BL, Soares NP, Santiago SS, Martins VT, Câmara RSB, Jesus MM, Tavares GSV, Ramos FF, Ludolf F, Magalhães LND, Oliveira FM, Duarte MC, Chávez-Fumagalli MA, Costa AV, Roatt BM, Teixeira RR, Coelho EAF. Freitas CS, et al. Among authors: oliveira fm. Cytokine. 2024 May;177:156543. doi: 10.1016/j.cyto.2024.156543. Epub 2024 Feb 18. Cytokine. 2024. PMID: 38373365
In vitro evaluation of antileishmanial activity, mode of action and cellular response induced by vanillin synthetic derivatives against Leishmania species able to cause cutaneous and visceral leishmaniasis.
Freitas CS, Santiago SS, Lage DP, Antinarelli LMR, Oliveira FM, Vale DL, Martins VT, Magalhaes LND, Bandeira RS, Ramos FF, Pereira IAG, de Jesus MM, Ludolf F, Tavares GSV, Costa AV, Ferreira RS, Coimbra ES, Teixeira RR, Coelho EAF. Freitas CS, et al. Among authors: oliveira fm. Exp Parasitol. 2023 Aug;251:108555. doi: 10.1016/j.exppara.2023.108555. Epub 2023 May 27. Exp Parasitol. 2023. PMID: 37247802
Treatment using vanillin-derived synthetic molecules incorporated into polymeric micelles is effective against infection caused by Leishmania amazonensis species.
Pereira IAG, Freitas CS, Câmara RSB, Jesus MM, Lage DP, Tavares GSV, Soyer TG, Ramos FF, Soares NP, Santiago SS, Martins VT, Vale DL, Pimenta BL, Ludolf F, Oliveira FM, Duarte MC, Chávez-Fumagalli MA, Costa AV, Gonçalves DU, Roatt BM, Teixeira RR, Coelho EAF. Pereira IAG, et al. Among authors: oliveira fm. Exp Parasitol. 2024 Mar 19;260:108743. doi: 10.1016/j.exppara.2024.108743. Online ahead of print. Exp Parasitol. 2024. PMID: 38513973
Comorbidity associated to Ascaris suum infection during pulmonary fibrosis exacerbates chronic lung and liver inflammation and dysfunction but not affect the parasite cycle in mice.
Oliveira FMS, da Paixão Matias PH, Kraemer L, Gazzinelli-Guimarães AC, Santos FV, Amorim CCO, Nogueira DS, Freitas CS, Caliari MV, Bartholomeu DC, Bueno LL, Russo RC, Fujiwara RT. Oliveira FMS, et al. PLoS Negl Trop Dis. 2019 Nov 25;13(11):e0007896. doi: 10.1371/journal.pntd.0007896. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31765381 Free PMC article.
Inhalation of dimethyl fumarate-encapsulated solid lipid nanoparticles attenuate clinical signs of experimental autoimmune encephalomyelitis and pulmonary inflammatory dysfunction in mice.
Pinto BF, Ribeiro LNB, da Silva GBRF, Freitas CS, Kraemer L, Oliveira FMS, Clímaco MC, Mourão FAG, Santos GSPD, Béla SR, Gurgel ILDS, Leite FL, de Oliveira AG, Vilela MRSDP, Oliveira-Lima OC, Soriani FM, Fujiwara RT, Birbrair A, Russo RC, Carvalho-Tavares J. Pinto BF, et al. Among authors: oliveira lima oc, oliveira fms. Clin Sci (Lond). 2022 Jan 14;136(1):81-101. doi: 10.1042/CS20210792. Clin Sci (Lond). 2022. PMID: 34904644
Detrimental role of IL-33/ST2 pathway sustaining a chronic eosinophil-dependent Th2 inflammatory response, tissue damage and parasite burden during Toxocara canis infection in mice.
Leal-Silva T, Vieira-Santos F, Oliveira FMS, Padrão LLS, Kraemer L, da Paixão Matias PH, de Almeida Lopes C, Loiola Ruas AC, de Azevedo IC, Nogueira DS, Rachid MA, Caliari MV, Castro Russo R, Fujiwara RT, Bueno LL. Leal-Silva T, et al. PLoS Negl Trop Dis. 2021 Jul 29;15(7):e0009639. doi: 10.1371/journal.pntd.0009639. eCollection 2021 Jul. PLoS Negl Trop Dis. 2021. PMID: 34324507 Free PMC article.
ASCVac-1, a Multi-Peptide Chimeric Vaccine, Protects Mice Against Ascaris suum Infection.
Gazzinelli-Guimarães AC, Nogueira DS, Amorim CCO, Oliveira FMS, Coqueiro-Dos-Santos A, Carvalho SAP, Kraemer L, Barbosa FS, Fraga VG, Santos FV, de Castro JC, Russo RC, Akamatsu MA, Ho PL, Bottazzi ME, Hotez PJ, Zhan B, Bartholomeu DC, Bueno LL, Fujiwara RT. Gazzinelli-Guimarães AC, et al. Front Immunol. 2021 Dec 21;12:788185. doi: 10.3389/fimmu.2021.788185. eCollection 2021. Front Immunol. 2021. PMID: 34992603 Free PMC article.
α-Gal immunization positively impacts Trypanosoma cruzi colonization of heart tissue in a mouse model.
Rodrigues da Cunha GM, Azevedo MA, Nogueira DS, Clímaco MC, Valencia Ayala E, Jimenez Chunga JA, La Valle RJY, da Cunha Galvão LM, Chiari E, Brito CRN, Soares RP, Nogueira PM, Fujiwara RT, Gazzinelli R, Hincapie R, Chaves CS, Oliveira FMS, Finn MG, Marques AF. Rodrigues da Cunha GM, et al. PLoS Negl Trop Dis. 2021 Jul 27;15(7):e0009613. doi: 10.1371/journal.pntd.0009613. eCollection 2021 Jul. PLoS Negl Trop Dis. 2021. PMID: 34314435 Free PMC article.
Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis.
Clímaco MC, de Figueiredo LA, Lucas RC, Pinheiro GRG, Dias Magalhães LM, Oliveira ALG, Almeida RM, Barbosa FS, Castanheira Bartholomeu D, Bueno LL, Mendes TA, Zhan B, Jones KM, Hotez P, Bottazzi ME, Oliveira FMS, Fujiwara RT. Clímaco MC, et al. Vaccine. 2023 Aug 23;41(37):5400-5411. doi: 10.1016/j.vaccine.2023.07.020. Epub 2023 Jul 20. Vaccine. 2023. PMID: 37479612
277 results