Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

543 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model.
Hoveyda HR, Fraser GL, Zoute L, Dutheuil G, Schils D, Brantis C, Lapin A, Parcq J, Guitard S, Lenoir F, Bousmaqui ME, Rorive S, Hospied S, Blanc S, Bernard J, Ooms F, McNelis JC, Olefsky JM. Hoveyda HR, et al. Among authors: olefsky jm. Bioorg Med Chem. 2018 Oct 1;26(18):5169-5180. doi: 10.1016/j.bmc.2018.09.015. Epub 2018 Sep 18. Bioorg Med Chem. 2018. PMID: 30253886
Macrophages, immunity, and metabolic disease.
McNelis JC, Olefsky JM. McNelis JC, et al. Among authors: olefsky jm. Immunity. 2014 Jul 17;41(1):36-48. doi: 10.1016/j.immuni.2014.05.010. Immunity. 2014. PMID: 25035952 Free article. Review.
GPR43 Potentiates β-Cell Function in Obesity.
McNelis JC, Lee YS, Mayoral R, van der Kant R, Johnson AM, Wollam J, Olefsky JM. McNelis JC, et al. Among authors: olefsky jm. Diabetes. 2015 Sep;64(9):3203-17. doi: 10.2337/db14-1938. Epub 2015 May 28. Diabetes. 2015. PMID: 26023106 Free PMC article.
Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.
Vu CB, Bemis JE, Disch JS, Ng PY, Nunes JJ, Milne JC, Carney DP, Lynch AV, Smith JJ, Lavu S, Lambert PD, Gagne DJ, Jirousek MR, Schenk S, Olefsky JM, Perni RB. Vu CB, et al. Among authors: olefsky jm. J Med Chem. 2009 Mar 12;52(5):1275-83. doi: 10.1021/jm8012954. J Med Chem. 2009. PMID: 19199480
A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Oh DY, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, McNelis J, Bogner-Strauss JG, Olefsky JM. Oh DY, et al. Among authors: olefsky jm. Nat Med. 2014 Aug;20(8):942-7. doi: 10.1038/nm.3614. Epub 2014 Jul 6. Nat Med. 2014. PMID: 24997608 Free PMC article.
Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity.
Mayoral R, Osborn O, McNelis J, Johnson AM, Oh DY, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, Olefsky JM. Mayoral R, et al. Among authors: olefsky jm. Mol Metab. 2015 Mar 5;4(5):378-91. doi: 10.1016/j.molmet.2015.02.007. eCollection 2015 May. Mol Metab. 2015. PMID: 25973386 Free PMC article.
543 results