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Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammation.
Bruno F, Errico S, Pace S, Nawrozkij MB, Mkrtchyan AS, Guida F, Maisto R, Olgaç A, D'Amico M, Maione S, De Rosa M, Banoglu E, Werz O, Fiorentino A, Filosa R. Bruno F, et al. Among authors: olgac a. Eur J Med Chem. 2018 Jul 15;155:946-960. doi: 10.1016/j.ejmech.2018.05.041. Epub 2018 May 28. Eur J Med Chem. 2018. PMID: 30015253
Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors.
Boccellino M, Donniacuo M, Bruno F, Rinaldi B, Quagliuolo L, Ambruosi M, Pace S, De Rosa M, Olgaç A, Banoglu E, Alessio N, Massa A, Kahn H, Werz O, Fiorentino A, Filosa R. Boccellino M, et al. Among authors: olgac a. Eur J Med Chem. 2019 Oct 15;180:637-647. doi: 10.1016/j.ejmech.2019.07.033. Epub 2019 Jul 10. Eur J Med Chem. 2019. PMID: 31351395
45 results