Okour M - Search Results

1

Drug Combination Modeling: Methods and Applications in Drug Development.

Pearson RA, Wicha SG, Okour M. Pearson RA, et al. Among authors: okour m. J Clin Pharmacol. 2023 Feb;63(2):151-165. doi: 10.1002/jcph.2128. Epub 2022 Sep 11. J Clin Pharmacol. 2023. PMID: 36088583 Review.

2

A human microdose study of the antimalarial drug GSK3191607 in healthy volunteers.

Okour M, Derimanov G, Barnett R, Fernandez E, Ferrer S, Gresham S, Hossain M, Gamo FJ, Koh G, Pereira A, Rolfe K, Wong D, Young G, Rami H, Haselden J. Okour M, et al. Br J Clin Pharmacol. 2018 Mar;84(3):482-489. doi: 10.1111/bcp.13476. Epub 2017 Dec 29. Br J Clin Pharmacol. 2018. PMID: 29168205 Free PMC article. Clinical Trial.

3

Mycophenolic Acid and Its Metabolites in Kidney Transplant Recipients: A Semimechanistic Enterohepatic Circulation Model to Improve Estimating Exposure.

Okour M, Jacobson PA, Ahmed MA, Israni AK, Brundage RC. Okour M, et al. J Clin Pharmacol. 2018 May;58(5):628-639. doi: 10.1002/jcph.1064. Epub 2018 Jan 12. J Clin Pharmacol. 2018. PMID: 29329489 Free PMC article.

4

A population analysis of the DGAT1 inhibitor GSK3008356 and its effect on endogenous and meal-induced triglyceride turnover in healthy subjects.

Okour M, Brigandi RA, Tenero D. Okour M, et al. Fundam Clin Pharmacol. 2019 Oct;33(5):567-580. doi: 10.1111/fcp.12455. Epub 2019 Mar 7. Fundam Clin Pharmacol. 2019. PMID: 30790345 Clinical Trial.

5

Evaluation of Potential Therapeutic Options for COVID-19.

Austin D, Okour M. Austin D, et al. Among authors: okour m. J Clin Pharmacol. 2020 Aug;60(8):976-977. doi: 10.1002/jcph.1669. Epub 2020 Jul 8. J Clin Pharmacol. 2020. PMID: 32469418 Free PMC article. No abstract available.

6

DosePredict: A Shiny Application for Generalized Pharmacokinetics-Based Dose Predictions.

Okour M. Okour M. J Clin Pharmacol. 2020 Nov;60(11):1502-1508. doi: 10.1002/jcph.1649. Epub 2020 Jun 15. J Clin Pharmacol. 2020. PMID: 32542731

7

Pediatric Population Pharmacokinetic Modeling and Exposure-Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data.

Okour M, Thapar MM, Farrell C, Lukas MA, Beghetti M, Beerahee M. Okour M, et al. J Clin Pharmacol. 2023 May;63(5):593-603. doi: 10.1002/jcph.2199. Epub 2023 Jan 29. J Clin Pharmacol. 2023. PMID: 36579617

8

Orphan drug development: the increasing role of clinical pharmacology.

Ahmed MA, Okour M, Brundage R, Kartha RV. Ahmed MA, et al. Among authors: okour m. J Pharmacokinet Pharmacodyn. 2019 Oct;46(5):395-409. doi: 10.1007/s10928-019-09646-3. Epub 2019 Jul 23. J Pharmacokinet Pharmacodyn. 2019. PMID: 31338634 Review.

9

A Gallbladder-Based Enterohepatic Circulation Model for Pharmacokinetic Studies.

Okour M, Brundage RC. Okour M, et al. Eur J Drug Metab Pharmacokinet. 2019 Aug;44(4):493-504. doi: 10.1007/s13318-018-0535-1. Eur J Drug Metab Pharmacokinet. 2019. PMID: 30488336

10

A Phase I Study to Show the Relative Bioavailability and Bioequivalence of Fixed-Dose Combinations of Ambrisentan and Tadalafil in Healthy Subjects.

Okour M, Puri A, Chen G, Port K, Berni A, Khindri S, Schneider I, Tenero D. Okour M, et al. Clin Ther. 2019 Jun;41(6):1110-1127. doi: 10.1016/j.clinthera.2019.04.007. Epub 2019 May 4. Clin Ther. 2019. PMID: 31060740 Clinical Trial.

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