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Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
Tang Q, Fakih HH, Zain Ui Abideen M, Hildebrand SR, Afshari K, Gross KY, Sousa J, Maebius AS, Bartholdy C, Søgaard PP, Jackerott M, Hariharan V, Summers A, Fan X, Okamura K, Monopoli KR, Cooper DA, Echeverria D, Bramato B, McHugh N, Furgal RC, Dresser K, Winter SJ, Biscans A, Chuprin J, Haddadi NS, Sherman S, Yıldız-Altay Ü, Rashighi M, Richmond JM, Bouix-Peter C, Blanchard C, Clauss A, Alterman JF, Khvorova A, Harris JE. Tang Q, et al. Among authors: okamura k. Nat Commun. 2023 Nov 4;14(1):7099. doi: 10.1038/s41467-023-42714-4. Nat Commun. 2023. PMID: 37925520 Free PMC article.
AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
Fukuda K, Okamura K, Riding RL, Fan X, Afshari K, Haddadi NS, McCauley SM, Guney MH, Luban J, Funakoshi T, Yaguchi T, Kawakami Y, Khvorova A, Fitzgerald KA, Harris JE. Fukuda K, et al. Among authors: okamura k. J Exp Med. 2021 Sep 6;218(9):e20200962. doi: 10.1084/jem.20200962. Epub 2021 Jul 29. J Exp Med. 2021. PMID: 34325468 Free PMC article.
RNAi-based modulation of IFN-γ signaling in skin.
Tang Q, Sousa J, Echeverria D, Fan X, Hsueh YC, Afshari K, MeHugh N, Cooper DA, Vangjeli L, Monopoli K, Okamura K, Biscans A, Clauss A, Harris JE, Khvorova A. Tang Q, et al. Among authors: okamura k. Mol Ther. 2022 Aug 3;30(8):2709-2721. doi: 10.1016/j.ymthe.2022.04.019. Epub 2022 Apr 27. Mol Ther. 2022. PMID: 35477658 Free PMC article.
Post-COVID-19 vaccination diffuse cutaneous sarcoidosis.
Hemmi A, Okamura K, Nikaido M, Saito T, Arai Y, Suzuki T. Hemmi A, et al. Among authors: okamura k. J Dermatol. 2024 Mar 14. doi: 10.1111/1346-8138.17194. Online ahead of print. J Dermatol. 2024. PMID: 38482893 No abstract available.
1,725 results