Okafor CD - Search Results

1

Bile acids and the gut microbiota: metabolic interactions and impacts on disease.

Collins SL, Stine JG, Bisanz JE, Okafor CD, Patterson AD. Collins SL, et al. Among authors: okafor cd. Nat Rev Microbiol. 2023 Apr;21(4):236-247. doi: 10.1038/s41579-022-00805-x. Epub 2022 Oct 17. Nat Rev Microbiol. 2023. PMID: 36253479 Review.

2

Identification of an Evolutionarily Conserved Allosteric Network in Steroid Receptors.

Dube N, Khan SH, Sasse R, Okafor CD. Dube N, et al. Among authors: okafor cd. J Chem Inf Model. 2023 Jan 23;63(2):571-582. doi: 10.1021/acs.jcim.2c01096. Epub 2023 Jan 3. J Chem Inf Model. 2023. PMID: 36594606 Free PMC article.

3

Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis.

Braffman NR, Ruskoski TB, Davis KM, Glasser NR, Johnson C, Okafor CD, Boal AK, Balskus EP. Braffman NR, et al. Among authors: okafor cd. Elife. 2022 Feb 25;11:e75761. doi: 10.7554/eLife.75761. Elife. 2022. PMID: 35212625 Free PMC article.

4

Ligand-induced shifts in conformational ensembles that describe transcriptional activation.

Khan SH, Braet SM, Koehler SJ, Elacqua E, Anand GS, Okafor CD. Khan SH, et al. Among authors: okafor cd. Elife. 2022 Oct 12;11:e80140. doi: 10.7554/eLife.80140. Elife. 2022. PMID: 36222302 Free PMC article.

5

Ancestral sequence reconstruction for evolutionary characterization of proteins.

Dube N, Khan SH, Okafor CD. Dube N, et al. Among authors: okafor cd. Trends Biochem Sci. 2022 Jan;47(1):98-99. doi: 10.1016/j.tibs.2021.10.009. Epub 2021 Nov 19. Trends Biochem Sci. 2022. PMID: 34810082 No abstract available.

6

Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of the N-nitrosourea-producing enzyme SznF.

McBride MJ, Pope SR, Hu K, Okafor CD, Balskus EP, Bollinger JM Jr, Boal AK. McBride MJ, et al. Among authors: okafor cd. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2015931118. doi: 10.1073/pnas.2015931118. Proc Natl Acad Sci U S A. 2021. PMID: 33468680 Free PMC article.

7

How nuclear receptors transition between active and inactive forms: An energetic perspective.

Hazarika S, Fehrle M, Okafor CD. Hazarika S, et al. Among authors: okafor cd. J Chem Phys. 2024 Mar 21;160(11):115102. doi: 10.1063/5.0189234. J Chem Phys. 2024. PMID: 38501469

8

Structure and Dynamics of the Liver Receptor Homolog 1-PGC1α Complex.

Mays SG, Okafor CD, Tuntland ML, Whitby RJ, Dharmarajan V, Stec J, Griffin PR, Ortlund EA. Mays SG, et al. Among authors: okafor cd. Mol Pharmacol. 2017 Jul;92(1):1-11. doi: 10.1124/mol.117.108514. Epub 2017 Mar 31. Mol Pharmacol. 2017. PMID: 28363985 Free PMC article.

9

A phospholipid mimetic targeting LRH-1 ameliorates colitis.

Mays SG, D'Agostino EH, Flynn AR, Huang X, Wang G, Liu X, Millings EJ, Okafor CD, Patel A, Cato ML, Cornelison JL, Melchers D, Houtman R, Moore DD, Calvert JW, Jui NT, Ortlund EA. Mays SG, et al. Among authors: okafor cd. Cell Chem Biol. 2022 Jul 21;29(7):1174-1186.e7. doi: 10.1016/j.chembiol.2022.03.001. Epub 2022 Mar 21. Cell Chem Biol. 2022. PMID: 35316658 Free article.

10

Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket.

Cato ML, Cornelison JL, Spurlin RM, Courouble VV, Patel AB, Flynn AR, Johnson AM, Okafor CD, Frank F, D'Agostino EH, Griffin PR, Jui NT, Ortlund EA. Cato ML, et al. Among authors: okafor cd. J Med Chem. 2022 May 12;65(9):6888-6902. doi: 10.1021/acs.jmedchem.2c00235. Epub 2022 May 3. J Med Chem. 2022. PMID: 35503419 Free PMC article.

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