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Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring.
Sun J, Esplugues E, Bort A, Cardelo MP, Ruz-Maldonado I, Fernández-Tussy P, Wong C, Wang H, Ojima I, Kaczocha M, Perry R, Suárez Y, Fernández-Hernando C. Sun J, et al. Among authors: ojima i. Nat Metab. 2024 Apr;6(4):741-763. doi: 10.1038/s42255-024-01019-6. Epub 2024 Apr 25. Nat Metab. 2024. PMID: 38664583
Combination therapy of itraconazole and an acylhydrazone derivative (D13) for the treatment of sporotrichosis in cats.
Dib Ferreira Gremião I, Pereira-Oliveira GR, Pereira SA, Corrêa ML, Borba-Santos LP, Viçosa AL, Garg A, Haranahalli K, Dasilva D, Pereira de Sa N, Matos GS, Silva V, Lazzarini C, Fernandes CM, Miranda K, Artunduaga Bonilla JJ, Nunes AL, Nimrichter L, Ojima I, Mallamo J, McCarthy JB, Del Poeta M. Dib Ferreira Gremião I, et al. Among authors: ojima i. Microbiol Spectr. 2024 Apr 22:e0396723. doi: 10.1128/spectrum.03967-23. Online ahead of print. Microbiol Spectr. 2024. PMID: 38647345 Free article.
Third-generation taxanes SB-T-121605 and SB-T-121606 are effective in pancreatic ductal adenocarcinoma.
Sychra T, Spalenkova A, Balatka S, Vaclavikova R, Seborova K, Ehrlichova M, Truksa J, Sandoval-Acuña C, Nemcova V, Szabo A, Koci K, Tesarova T, Chen L, Ojima I, Oliverius M, Soucek P. Sychra T, et al. Among authors: ojima i. iScience. 2024 Jan 26;27(2):109044. doi: 10.1016/j.isci.2024.109044. eCollection 2024 Feb 16. iScience. 2024. PMID: 38357661 Free PMC article.
Discovery and Preclinical Evaluation of a Novel Inhibitor of FABP5, ART26.12, Effective in Oxaliplatin-Induced Peripheral Neuropathy.
Warren G, Osborn M, Tsantoulas C, David-Pereira A, Cohn D, Duffy P, Ruston L, Johnson C, Bradshaw H, Kaczocha M, Ojima I, Yates A, O'Sullivan SE. Warren G, et al. Among authors: ojima i. J Pain. 2024 Jan 15:S1526-5900(24)00345-6. doi: 10.1016/j.jpain.2024.01.335. Online ahead of print. J Pain. 2024. PMID: 38232863 Free article.
FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate Cancer.
M Swamynathan M, Mathew G, Aziz A, Gordon C, Hillowe A, Wang H, Jhaveri A, Kendall J, Cox H, Giarrizzo M, Azabdaftari G, Rizzo RC, Diermeier SD, Ojima I, Bialkowska AB, Kaczocha M, Trotman LC. M Swamynathan M, et al. Among authors: ojima i. Cancers (Basel). 2023 Dec 21;16(1):60. doi: 10.3390/cancers16010060. Cancers (Basel). 2023. PMID: 38201488 Free PMC article.
Fatty acid binding protein 5 inhibition attenuates pronociceptive cytokine/chemokine expression and suppresses osteoarthritis pain: A comparative human and rat study.
Gordon C, Trainor J, Shah RJ, Studholme K, Gelman A, Doswell F, Sadar F, Giovannetti A, Gershenson J, Khan A, Nicholson J, Huang Z, Spurgat M, Tang SJ, Wang H, Ojima I, Carlson D, Komatsu DE, Kaczocha M. Gordon C, et al. Among authors: ojima i. Osteoarthritis Cartilage. 2024 Mar;32(3):266-280. doi: 10.1016/j.joca.2023.11.010. Epub 2023 Nov 28. Osteoarthritis Cartilage. 2024. PMID: 38035977
223 results