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The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.
Life Sci Alliance. 2023 Jan 31;6(4):e202201644. doi: 10.26508/lsa.202201644. Print 2023 Apr.
Life Sci Alliance. 2023.
PMID: 36720499
Free PMC article.
iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.
Oikonomidi I, Burbridge E, Cavadas M, Sullivan G, Collis B, Naegele H, Clancy D, Brezinova J, Hu T, Bileck A, Gerner C, Bolado A, von Kriegsheim A, Martin SJ, Steinberg F, Strisovsky K, Adrain C.
Oikonomidi I, et al.
Elife. 2018 Jun 13;7:e35032. doi: 10.7554/eLife.35032.
Elife. 2018.
PMID: 29897333
Free PMC article.
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Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.
Cavadas M, Oikonomidi I, Gaspar CJ, Burbridge E, Badenes M, Félix I, Bolado A, Hu T, Bileck A, Gerner C, Domingos PM, von Kriegsheim A, Adrain C.
Cavadas M, et al. Among authors: oikonomidi i.
Cell Rep. 2017 Oct 17;21(3):745-757. doi: 10.1016/j.celrep.2017.09.074.
Cell Rep. 2017.
PMID: 29045841
Free PMC article.
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