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Impaired lymphocyte trafficking in mice deficient in the kinase activity of PKN1.
Mashud R, Nomachi A, Hayakawa A, Kubouchi K, Danno S, Hirata T, Matsuo K, Nakayama T, Satoh R, Sugiura R, Abe M, Sakimura K, Wakana S, Ohsaki H, Kamoshida S, Mukai H. Mashud R, et al. Among authors: ohsaki h. Sci Rep. 2017 Aug 9;7(1):7663. doi: 10.1038/s41598-017-07936-9. Sci Rep. 2017. PMID: 28794483 Free PMC article.
PKN1 kinase-negative knock-in mice develop splenomegaly and leukopenia at advanced age without obvious autoimmune-like phenotypes.
Siddique SM, Kubouchi K, Shinmichi Y, Sawada N, Sugiura R, Itoh Y, Uehara S, Nishimura K, Okamura S, Ohsaki H, Kamoshida S, Yamashita Y, Tamura S, Sonoki T, Matsuoka H, Itoh T, Mukai H. Siddique SM, et al. Among authors: ohsaki h. Sci Rep. 2019 Sep 27;9(1):13977. doi: 10.1038/s41598-019-50419-2. Sci Rep. 2019. PMID: 31562379 Free PMC article.
91 results