Ohbuchi M - Search Results

1

Preclinical Characterization of ASP2713, a Novel Igβ and FcγRIIB Cross-Linking Antibody, for Prediction of Human Pharmacokinetics and Clinically Effective Dose.

Konishi K, Nakamura K, Hanada Y, Kitanaga Y, Kubo S, Kinugasa F, Yamajuku D, Maeda M, Yamamoto N, Minematsu T, Ohbuchi M, Kondo Y, Sumida T. Konishi K, et al. Among authors: ohbuchi m. J Pharm Sci. 2022 Sep;111(9):2630-2638. doi: 10.1016/j.xphs.2022.06.006. Epub 2022 Jun 11. J Pharm Sci. 2022. PMID: 35700799

2

Modelling and Prevention of Acute Kidney Injury through Ischemia and Reperfusion in a Combined Human Renal Proximal Tubule/Blood Vessel-on-a-Chip.

Vormann MK, Tool LM, Ohbuchi M, Gijzen L, van Vught R, Hankemeier T, Kiyonaga F, Kawabe T, Goto T, Fujimori A, Vulto P, Lanz HL, Tetsuka K. Vormann MK, et al. Among authors: ohbuchi m. Kidney360. 2021 Nov 4;3(2):217-231. doi: 10.34067/KID.0003622021. eCollection 2022 Feb 24. Kidney360. 2021. PMID: 35373131 Free PMC article.

3

Reconstituted Human Organ Models as a Translational Tool for Human Organ Response: Definition, Expectations, Cases, and Strategies for Implementation in Drug Discovery and Development.

Tetsuka K, Ohbuchi M, Kawabe T, Goto T, Kiyonaga F, Takama K, Yamazaki S, Fujimori A. Tetsuka K, et al. Among authors: ohbuchi m. Biol Pharm Bull. 2020;43(3):375-383. doi: 10.1248/bpb.b19-01070. Biol Pharm Bull. 2020. PMID: 32115499 Free article. Review.

4

[Application of novel 3D-bioprinted human liver tissue models in drug discovery research].

Ohbuchi M. Ohbuchi M. Nihon Yakurigaku Zasshi. 2019;153(6):284-288. doi: 10.1254/fpj.153.284. Nihon Yakurigaku Zasshi. 2019. PMID: 31178534 Review. Japanese.

5

Neuroprotective Effects of Fasudil, a Rho-Kinase Inhibitor, After Spinal Cord Ischemia and Reperfusion in Rats.

Ohbuchi M, Kimura T, Nishikawa T, Horiguchi T, Fukuda M, Masaki Y. Ohbuchi M, et al. Anesth Analg. 2018 Mar;126(3):815-823. doi: 10.1213/ANE.0000000000002602. Anesth Analg. 2018. PMID: 29099428

6

Recent Progress in Hepatocyte Culture Models and Their Application to the Assessment of Drug Metabolism, Transport, and Toxicity in Drug Discovery: The Value of Tissue Engineering for the Successful Development of a Microphysiological System.

Tetsuka K, Ohbuchi M, Tabata K. Tetsuka K, et al. Among authors: ohbuchi m. J Pharm Sci. 2017 Sep;106(9):2302-2311. doi: 10.1016/j.xphs.2017.05.010. Epub 2017 May 19. J Pharm Sci. 2017. PMID: 28533121 Review.

7

Murine Cyp3a knockout chimeric mice with humanized liver: prediction of the metabolic profile of nefazodone in humans.

Nakada N, Kawamura A, Kamimura H, Sato K, Kazuki Y, Kakuni M, Ohbuchi M, Kato K, Tateno C, Oshimura M, Usui T. Nakada N, et al. Among authors: ohbuchi m. Biopharm Drug Dispos. 2016 Jan;37(1):3-14. doi: 10.1002/bdd.1990. Biopharm Drug Dispos. 2016. PMID: 26352195

8

Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver.

Kato K, Ohbuchi M, Hamamura S, Ohshita H, Kazuki Y, Oshimura M, Sato K, Nakada N, Kawamura A, Usui T, Kamimura H, Tateno C. Kato K, et al. Among authors: ohbuchi m. Drug Metab Dispos. 2015 Aug;43(8):1208-17. doi: 10.1124/dmd.115.063479. Epub 2015 May 15. Drug Metab Dispos. 2015. PMID: 25979261

9

Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.

Ohbuchi M, Yoshinari K, Kaneko H, Matsumoto S, Inoue A, Kawamura A, Usui T, Yamazoe Y. Ohbuchi M, et al. Antimicrob Agents Chemother. 2013 Mar;57(3):1332-8. doi: 10.1128/AAC.01900-12. Epub 2012 Dec 28. Antimicrob Agents Chemother. 2013. PMID: 23274663 Free PMC article.

10

Different effects of proton pump inhibitors and famotidine on the clopidogrel metabolic activation by recombinant CYP2B6, CYP2C19 and CYP3A4.

Ohbuchi M, Noguchi K, Kawamura A, Usui T. Ohbuchi M, et al. Xenobiotica. 2012 Jul;42(7):633-40. doi: 10.3109/00498254.2011.653655. Epub 2012 Feb 7. Xenobiotica. 2012. PMID: 22313038

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