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Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy.
Boukhaled GM, Gadalla R, Elsaesser HJ, Abd-Rabbo D, Quevedo R, Yang SYC, Guo M, Wang BX, Noamani B, Gray D, Lau SCM, Taylor K, Aung K, Spreafico A, Hansen AR, Saibil SD, Hirano N, Guidos C, Pugh TJ, McGaha TL, Ohashi PS, Sacher AG, Butler MO, Brooks DG. Boukhaled GM, et al. Among authors: ohashi ps. Nat Immunol. 2022 Aug;23(8):1273-1283. doi: 10.1038/s41590-022-01262-7. Epub 2022 Jul 14. Nat Immunol. 2022. PMID: 35835962
Weak agonist self-peptides promote selection and tuning of virus-specific T cells.
Saibil SD, Ohteki T, White FM, Luscher M, Zakarian A, Elford A, Shabanowitz J, Nishina H, Hugo P, Penninger J, Barber B, Hunt DF, Ohashi PS. Saibil SD, et al. Among authors: ohashi ps. Eur J Immunol. 2003 Mar;33(3):685-96. doi: 10.1002/eji.200323143. Eur J Immunol. 2003. PMID: 12616489 Free article.
The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses.
Suh WK, Gajewska BU, Okada H, Gronski MA, Bertram EM, Dawicki W, Duncan GS, Bukczynski J, Plyte S, Elia A, Wakeham A, Itie A, Chung S, Da Costa J, Arya S, Horan T, Campbell P, Gaida K, Ohashi PS, Watts TH, Yoshinaga SK, Bray MR, Jordana M, Mak TW. Suh WK, et al. Among authors: ohashi ps. Nat Immunol. 2003 Sep;4(9):899-906. doi: 10.1038/ni967. Epub 2003 Aug 17. Nat Immunol. 2003. PMID: 12925852
The sound of silence: modulating anergy in T lymphocytes.
Saibil SD, Deenick EK, Ohashi PS. Saibil SD, et al. Among authors: ohashi ps. Curr Opin Immunol. 2007 Dec;19(6):658-64. doi: 10.1016/j.coi.2007.08.005. Epub 2007 Oct 18. Curr Opin Immunol. 2007. PMID: 17949964 Review.
327 results