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This Old Neighborhood Made M1 this Way.
Gruber F, Ogrodnik M. Gruber F, et al. Among authors: ogrodnik m. J Invest Dermatol. 2022 Dec;142(12):3131-3132. doi: 10.1016/j.jid.2022.07.014. Epub 2022 Sep 29. J Invest Dermatol. 2022. PMID: 36182528 Free article. No abstract available.
Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance.
Zhang X, Pearsall VM, Carver CM, Atkinson EJ, Clarkson BDS, Grund EM, Baez-Faria M, Pavelko KD, Kachergus JM, White TA, Johnson RK, Malo CS, Gonzalez-Suarez AM, Ayasoufi K, Johnson KO, Tritz ZP, Fain CE, Khadka RH, Ogrodnik M, Jurk D, Zhu Y, Tchkonia T, Revzin A, Kirkland JL, Johnson AJ, Howe CL, Thompson EA, LeBrasseur NK, Schafer MJ. Zhang X, et al. Among authors: ogrodnik m. Nat Commun. 2022 Sep 27;13(1):5671. doi: 10.1038/s41467-022-33226-8. Nat Commun. 2022. PMID: 36167854 Free PMC article.
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.
Xu M, Tchkonia T, Ding H, Ogrodnik M, Lubbers ER, Pirtskhalava T, White TA, Johnson KO, Stout MB, Mezera V, Giorgadze N, Jensen MD, LeBrasseur NK, Kirkland JL. Xu M, et al. Among authors: ogrodnik m. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6301-10. doi: 10.1073/pnas.1515386112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26578790 Free PMC article.
Identification of Senescent Cells in the Bone Microenvironment.
Farr JN, Fraser DG, Wang H, Jaehn K, Ogrodnik MB, Weivoda MM, Drake MT, Tchkonia T, LeBrasseur NK, Kirkland JL, Bonewald LF, Pignolo RJ, Monroe DG, Khosla S. Farr JN, et al. Among authors: ogrodnik mb. J Bone Miner Res. 2016 Nov;31(11):1920-1929. doi: 10.1002/jbmr.2892. Epub 2016 Oct 24. J Bone Miner Res. 2016. PMID: 27341653 Free PMC article.
Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice.
Xu M, Bradley EW, Weivoda MM, Hwang SM, Pirtskhalava T, Decklever T, Curran GL, Ogrodnik M, Jurk D, Johnson KO, Lowe V, Tchkonia T, Westendorf JJ, Kirkland JL. Xu M, et al. Among authors: ogrodnik m. J Gerontol A Biol Sci Med Sci. 2017 Jun 1;72(6):780-785. doi: 10.1093/gerona/glw154. J Gerontol A Biol Sci Med Sci. 2017. PMID: 27516624 Free PMC article.
Cellular senescence drives age-dependent hepatic steatosis.
Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, Day CP, Burt A, Palmer A, Anstee QM, Grellscheid SN, Hoeijmakers JHJ, Barnhoorn S, Mann DA, Bird TG, Vermeij WP, Kirkland JL, Passos JF, von Zglinicki T, Jurk D. Ogrodnik M, et al. Nat Commun. 2017 Jun 13;8:15691. doi: 10.1038/ncomms15691. Nat Commun. 2017. PMID: 28608850 Free PMC article.
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