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EOS789, a broad-spectrum inhibitor of phosphate transport, is safe with an indication of efficacy in a phase 1b randomized crossover trial in hemodialysis patients.
Hill Gallant KM, Stremke ER, Trevino LL, Moorthi RN, Doshi S, Wastney ME, Hisada N, Sato J, Ogita Y, Fujii N, Matsuda Y, Kake T, Moe SM. Hill Gallant KM, et al. Among authors: ogita y. Kidney Int. 2021 May;99(5):1225-1233. doi: 10.1016/j.kint.2020.09.035. Epub 2020 Oct 31. Kidney Int. 2021. PMID: 33137340 Free PMC article. Clinical Trial.
Phase I and pharmacokinetics/pharmacodynamics study of the MEK inhibitor RO4987655 in Japanese patients with advanced solid tumors.
Nakamichi S, Nokihara H, Yamamoto N, Yamada Y, Fujiwara Y, Tamura Y, Wakui H, Honda K, Mizugaki H, Kitazono S, Tanabe Y, Asahina H, Yamazaki N, Suzuki S, Matsuoka M, Ogita Y, Tamura T. Nakamichi S, et al. Among authors: ogita y. Invest New Drugs. 2015 Jun;33(3):641-51. doi: 10.1007/s10637-015-0229-3. Epub 2015 Mar 27. Invest New Drugs. 2015. PMID: 25809858 Clinical Trial.
Phase I and pharmacokinetic/pharmacodynamic study of RO5126766, a first-in-class dual Raf/MEK inhibitor, in Japanese patients with advanced solid tumors.
Honda K, Yamamoto N, Nokihara H, Tamura Y, Asahina H, Yamada Y, Suzuki S, Yamazaki N, Ogita Y, Tamura T. Honda K, et al. Among authors: ogita y. Cancer Chemother Pharmacol. 2013 Sep;72(3):577-84. doi: 10.1007/s00280-013-2228-4. Epub 2013 Jul 17. Cancer Chemother Pharmacol. 2013. PMID: 23860959 Clinical Trial.
Transforming mutations of RAC guanosine triphosphatases in human cancers.
Kawazu M, Ueno T, Kontani K, Ogita Y, Ando M, Fukumura K, Yamato A, Soda M, Takeuchi K, Miki Y, Yamaguchi H, Yasuda T, Naoe T, Yamashita Y, Katada T, Choi YL, Mano H. Kawazu M, et al. Among authors: ogita y. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3029-34. doi: 10.1073/pnas.1216141110. Epub 2013 Feb 4. Proc Natl Acad Sci U S A. 2013. PMID: 23382236 Free PMC article.
33 results