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Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH.
Itoh M, Tamura A, Kanai S, Tanaka M, Kanamori Y, Shirakawa I, Ito A, Oka Y, Hidaka I, Takami T, Honda Y, Maeda M, Saito Y, Murata Y, Matozaki T, Nakajima A, Kataoka Y, Ogi T, Ogawa Y, Suganami T. Itoh M, et al. Among authors: ogi t. J Exp Med. 2023 Nov 6;220(11):e20220681. doi: 10.1084/jem.20220681. Epub 2023 Sep 19. J Exp Med. 2023. PMID: 37725372 Free PMC article.
Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair.
Nakazawa Y, Hara Y, Oka Y, Komine O, van den Heuvel D, Guo C, Daigaku Y, Isono M, He Y, Shimada M, Kato K, Jia N, Hashimoto S, Kotani Y, Miyoshi Y, Tanaka M, Sobue A, Mitsutake N, Suganami T, Masuda A, Ohno K, Nakada S, Mashimo T, Yamanaka K, Luijsterburg MS, Ogi T. Nakazawa Y, et al. Among authors: ogi t. Cell. 2020 Mar 19;180(6):1228-1244.e24. doi: 10.1016/j.cell.2020.02.010. Epub 2020 Mar 5. Cell. 2020. PMID: 32142649 Free article.
Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction.
Konishi H, Okamoto T, Hara Y, Komine O, Tamada H, Maeda M, Osako F, Kobayashi M, Nishiyama A, Kataoka Y, Takai T, Udagawa N, Jung S, Ozato K, Tamura T, Tsuda M, Yamanaka K, Ogi T, Sato K, Kiyama H. Konishi H, et al. Among authors: ogi t. EMBO J. 2020 Nov 16;39(22):e104464. doi: 10.15252/embj.2020104464. Epub 2020 Sep 22. EMBO J. 2020. PMID: 32959911 Free PMC article.
Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome.
Oka Y, Hamada M, Nakazawa Y, Muramatsu H, Okuno Y, Higasa K, Shimada M, Takeshima H, Hanada K, Hirano T, Kawakita T, Sakaguchi H, Ichimura T, Ozono S, Yuge K, Watanabe Y, Kotani Y, Yamane M, Kasugai Y, Tanaka M, Suganami T, Nakada S, Mitsutake N, Hara Y, Kato K, Mizuno S, Miyake N, Kawai Y, Tokunaga K, Nagasaki M, Kito S, Isoyama K, Onodera M, Kaneko H, Matsumoto N, Matsuda F, Matsuo K, Takahashi Y, Mashimo T, Kojima S, Ogi T. Oka Y, et al. Among authors: ogi t. Sci Adv. 2020 Dec 18;6(51):eabd7197. doi: 10.1126/sciadv.abd7197. Print 2020 Dec. Sci Adv. 2020. PMID: 33355142 Free article.
The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model.
Yoshioka N, Tanaka M, Ochi K, Watanabe A, Ono K, Sawada M, Ogi T, Itoh M, Ito A, Shiraki Y, Enomoto A, Ishigami M, Fujishiro M, Ogawa Y, Suganami T. Yoshioka N, et al. Among authors: ogi t. Biomed Pharmacother. 2021 Aug;140:111738. doi: 10.1016/j.biopha.2021.111738. Epub 2021 May 21. Biomed Pharmacother. 2021. PMID: 34029949 Free article.
A case of non-immune hydrops fetalis with maternal mirror syndrome diagnosed by trio-based exome sequencing: An autopsy case report and literature review.
Tano S, Kotani T, Yoshihara M, Nakamura N, Matsuo S, Ushida T, Imai K, Ito M, Oka Y, Sato E, Hayashi S, Ogi T, Kajiyama H. Tano S, et al. Among authors: ogi t. Mol Genet Metab Rep. 2022 Oct 14;33:100925. doi: 10.1016/j.ymgmr.2022.100925. eCollection 2022 Dec. Mol Genet Metab Rep. 2022. PMID: 36274670 Free PMC article.
237 results