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Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer.
Jiang L, Huang J, Higgs BW, Hu Z, Xiao Z, Yao X, Conley S, Zhong H, Liu Z, Brohawn P, Shen D, Wu S, Ge X, Jiang Y, Zhao Y, Lou Y, Morehouse C, Zhu W, Sebastian Y, Czapiga M, Oganesyan V, Fu H, Niu Y, Zhang W, Streicher K, Tice D, Zhao H, Zhu M, Xu L, Herbst R, Su X, Gu Y, Li S, Huang L, Gu J, Han B, Jallal B, Shen H, Yao Y. Jiang L, et al. Among authors: oganesyan v. PLoS Genet. 2016 Apr 19;12(4):e1005895. doi: 10.1371/journal.pgen.1005895. eCollection 2016 Apr. PLoS Genet. 2016. PMID: 27093186 Free PMC article.
A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity.
Karnell JL, Albulescu M, Drabic S, Wang L, Moate R, Baca M, Oganesyan V, Gunsior M, Thisted T, Yan L, Li J, Xiong X, Eck SC, de Los Reyes M, Yusuf I, Streicher K, Müller-Ladner U, Howe D, Ettinger R, Herbst R, Drappa J. Karnell JL, et al. Among authors: oganesyan v. Sci Transl Med. 2019 Apr 24;11(489):eaar6584. doi: 10.1126/scitranslmed.aar6584. Sci Transl Med. 2019. PMID: 31019027
Fibronectin type III domains engineered to bind CD40L: cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of two complexes.
Oganesyan V, Ferguson A, Grinberg L, Wang L, Phipps S, Chacko B, Drabic S, Thisted T, Baca M. Oganesyan V, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Sep;69(Pt 9):1045-8. doi: 10.1107/S1744309113022847. Epub 2013 Aug 21. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23989160 Free PMC article.
Crystal structure of the human 4-1BB/4-1BBL complex.
Gilbreth RN, Oganesyan VY, Amdouni H, Novarra S, Grinberg L, Barnes A, Baca M. Gilbreth RN, et al. J Biol Chem. 2018 Jun 22;293(25):9880-9891. doi: 10.1074/jbc.RA118.002803. Epub 2018 May 2. J Biol Chem. 2018. PMID: 29720399 Free PMC article.
Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity In Vitro and Staphylococcus aureus Fitness in Infection Models.
Tkaczyk C, Semenova E, Shi YY, Rosenthal K, Oganesyan V, Warrener P, Stover CK, Sellman BR. Tkaczyk C, et al. Among authors: oganesyan v. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01033-18. doi: 10.1128/AAC.01033-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30150481 Free PMC article.
Generation and Characterization of an IgG4 Monomeric Fc Platform.
Shan L, Colazet M, Rosenthal KL, Yu XQ, Bee JS, Ferguson A, Damschroder MM, Wu H, Dall'Acqua WF, Tsui P, Oganesyan V. Shan L, et al. Among authors: oganesyan v. PLoS One. 2016 Aug 1;11(8):e0160345. doi: 10.1371/journal.pone.0160345. eCollection 2016. PLoS One. 2016. PMID: 27479095 Free PMC article.
Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.
Oganesyan V, Peng L, Bee JS, Li J, Perry SR, Comer F, Xu L, Cook K, Senthil K, Clarke L, Rosenthal K, Gao C, Damschroder M, Wu H, Dall'Acqua W. Oganesyan V, et al. J Biol Chem. 2018 Jun 1;293(22):8439-8448. doi: 10.1074/jbc.M117.818013. Epub 2018 Apr 18. J Biol Chem. 2018. PMID: 29669810 Free PMC article.
92 results