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Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Zeyen P, Zeyn Y, Herp D, Mahmoudi F, Yesiloglu TZ, Erdmann F, Schmidt M, Robaa D, Romier C, Ridinger J, Herbst-Gervasoni CJ, Christianson DW, Oehme I, Jung M, Krämer OH, Sippl W. Zeyen P, et al. Among authors: oehme i. Eur J Med Chem. 2022 Apr 15;234:114272. doi: 10.1016/j.ejmech.2022.114272. Epub 2022 Mar 11. Eur J Med Chem. 2022. PMID: 35306288 Free PMC article.
Histone deacetylase 8 in neuroblastoma tumorigenesis.
Oehme I, Deubzer HE, Wegener D, Pickert D, Linke JP, Hero B, Kopp-Schneider A, Westermann F, Ulrich SM, von Deimling A, Fischer M, Witt O. Oehme I, et al. Clin Cancer Res. 2009 Jan 1;15(1):91-9. doi: 10.1158/1078-0432.CCR-08-0684. Clin Cancer Res. 2009. PMID: 19118036
Targeting histone deacetylases in neuroblastoma.
Witt O, Deubzer HE, Lodrini M, Milde T, Oehme I. Witt O, et al. Among authors: oehme i. Curr Pharm Des. 2009;15(4):436-47. doi: 10.2174/138161209787315774. Curr Pharm Des. 2009. PMID: 19199971 Review.
HDAC11 is a novel drug target in carcinomas.
Deubzer HE, Schier MC, Oehme I, Lodrini M, Haendler B, Sommer A, Witt O. Deubzer HE, et al. Among authors: oehme i. Int J Cancer. 2013 May 1;132(9):2200-8. doi: 10.1002/ijc.27876. Epub 2012 Oct 25. Int J Cancer. 2013. PMID: 23024001 Free article.
Histone deacetylase 10 promotes autophagy-mediated cell survival.
Oehme I, Linke JP, Böck BC, Milde T, Lodrini M, Hartenstein B, Wiegand I, Eckert C, Roth W, Kool M, Kaden S, Gröne HJ, Schulte JH, Lindner S, Hamacher-Brady A, Brady NR, Deubzer HE, Witt O. Oehme I, et al. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2592-601. doi: 10.1073/pnas.1300113110. Epub 2013 Jun 25. Proc Natl Acad Sci U S A. 2013. PMID: 23801752 Free PMC article.
HDAC8: a multifaceted target for therapeutic interventions.
Chakrabarti A, Oehme I, Witt O, Oliveira G, Sippl W, Romier C, Pierce RJ, Jung M. Chakrabarti A, et al. Among authors: oehme i. Trends Pharmacol Sci. 2015 Jul;36(7):481-92. doi: 10.1016/j.tips.2015.04.013. Epub 2015 May 23. Trends Pharmacol Sci. 2015. PMID: 26013035 Free article. Review.
73 results