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Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study and volunteer infection study.
McCarthy JS, Yalkinoglu Ö, Odedra A, Webster R, Oeuvray C, Tappert A, Bezuidenhout D, Giddins MJ, Dhingra SK, Fidock DA, Marquart L, Webb L, Yin X, Khandelwal A, Bagchus WM. McCarthy JS, et al. Among authors: odedra a. Lancet Infect Dis. 2021 Dec;21(12):1713-1724. doi: 10.1016/S1473-3099(21)00252-8. Epub 2021 Oct 26. Lancet Infect Dis. 2021. PMID: 34715032 Free PMC article. Clinical Trial.
A Plasmodium vivax experimental human infection model for evaluating efficacy of interventions.
Collins KA, Wang CY, Adams M, Mitchell H, Robinson GJ, Rampton M, Elliott S, Odedra A, Khoury D, Ballard E, Shelper TB, Lucantoni L, Avery VM, Chalon S, Moehrle JJ, McCarthy JS. Collins KA, et al. Among authors: odedra a. J Clin Invest. 2020 Jun 1;130(6):2920-2927. doi: 10.1172/JCI134923. J Clin Invest. 2020. PMID: 32045385 Free PMC article. Clinical Trial.
Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: A pilot and a randomised volunteer infection study in Australia.
Watts RE, Odedra A, Marquart L, Webb L, Abd-Rahman AN, Cascales L, Chalon S, Rebelo M, Pava Z, Collins KA, Pasay C, Chen N, Peatey CL, Möhrle JJ, McCarthy JS. Watts RE, et al. Among authors: odedra a. PLoS Med. 2020 Aug 21;17(8):e1003203. doi: 10.1371/journal.pmed.1003203. eCollection 2020 Aug. PLoS Med. 2020. PMID: 32822347 Free PMC article. Clinical Trial.
Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine.
Webster R, Sekuloski S, Odedra A, Woolley S, Jennings H, Amante F, Trenholme KR, Healer J, Cowman AF, Eriksson EM, Sathe P, Penington J, Blanch AJ, Dixon MWA, Tilley L, Duffy MF, Craig A, Storm J, Chan JA, Evans K, Papenfuss AT, Schofield L, Griffin P, Barber BE, Andrew D, Boyle MJ, de Labastida Rivera F, Engwerda C, McCarthy JS. Webster R, et al. Among authors: odedra a. BMC Med. 2021 Nov 22;19(1):293. doi: 10.1186/s12916-021-02150-x. BMC Med. 2021. PMID: 34802442 Free PMC article. Clinical Trial.
36 results