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You BETer be aware - learnings from a negative Phase 1 study.
Postei-Vinoy S, Ocker M. Postei-Vinoy S, et al. Among authors: ocker m. Oncotarget. 2019 May 7;10(34):3145-3146. doi: 10.18632/oncotarget.26898. eCollection 2019 May 7. Oncotarget. 2019. PMID: 31139327 Free PMC article. No abstract available.
Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer.
Di Fazio P, Waldegger P, Jabari S, Lingelbach S, Montalbano R, Ocker M, Slater EP, Bartsch DK, Illig R, Neureiter D, Wissniowski TT. Di Fazio P, et al. Among authors: ocker m. Oncotarget. 2016 May 17;7(20):28998-9010. doi: 10.18632/oncotarget.8585. Oncotarget. 2016. PMID: 27058414 Free PMC article.
First-in-human phase I study of the bromodomain and extraterminal motif inhibitor BAY 1238097: emerging pharmacokinetic/pharmacodynamic relationship and early termination due to unexpected toxicity.
Postel-Vinay S, Herbschleb K, Massard C, Woodcock V, Soria JC, Walter AO, Ewerton F, Poelman M, Benson N, Ocker M, Wilkinson G, Middleton M. Postel-Vinay S, et al. Among authors: ocker m. Eur J Cancer. 2019 Mar;109:103-110. doi: 10.1016/j.ejca.2018.12.020. Epub 2019 Jan 31. Eur J Cancer. 2019. PMID: 30711772 Clinical Trial.
Phase 1 Dose Escalation Study of the Allosteric AKT Inhibitor BAY 1125976 in Advanced Solid Cancer-Lack of Association between Activating AKT Mutation and AKT Inhibition-Derived Efficacy.
Schneeweiss A, Hess D, Joerger M, Varga A, Moulder S, Tsimberidou AM, Ma C, Hurvitz SA, Rentzsch C, Rudolph M, Thiele S, Boix O, Wilkinson G, Lagkadinou E, Ocker M. Schneeweiss A, et al. Among authors: ocker m. Cancers (Basel). 2019 Dec 10;11(12):1987. doi: 10.3390/cancers11121987. Cancers (Basel). 2019. PMID: 31835495 Free PMC article.
Pathological impact of hepatitis B virus surface proteins on the liver is associated with the host genetic background.
Churin Y, Roderfeld M, Stiefel J, Würger T, Schröder D, Matono T, Mollenkopf HJ, Montalbano R, Pompaiah M, Reifenberg K, Zahner D, Ocker M, Gerlich W, Glebe D, Roeb E. Churin Y, et al. Among authors: ocker m. PLoS One. 2014 Mar 4;9(3):e90608. doi: 10.1371/journal.pone.0090608. eCollection 2014. PLoS One. 2014. PMID: 24594856 Free PMC article.
Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4-/- Mice.
Helmrich N, Roderfeld M, Baier A, Windhorst A, Herebian D, Mayatepek E, Dierkes C, Ocker M, Glebe D, Christ B, Churin Y, Irungbam K, Roeb E. Helmrich N, et al. Among authors: ocker m. Cell Mol Gastroenterol Hepatol. 2022;13(4):1041-1055. doi: 10.1016/j.jcmgh.2021.12.013. Epub 2021 Dec 23. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34954190 Free PMC article.
147 results