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Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia.
Canals I, Comella-Bolla A, Cepeda-Prado E, Avaliani N, Crowe JA, Oburoglu L, Bruzelius A, King N, Pajares MA, Pérez-Sala D, Heuer A, Rylander Ottosson D, Soriano J, Ahlenius H. Canals I, et al. Among authors: oburoglu l. Brain Commun. 2023 May 18;5(3):fcad158. doi: 10.1093/braincomms/fcad158. eCollection 2023. Brain Commun. 2023. PMID: 37274831 Free PMC article.
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity.
Rodriguez-Zabala M, Ramakrishnan R, Reinbach K, Ghosh S, Oburoglu L, Falqués-Costa A, Bellamkonda K, Ehinger M, Peña-Martínez P, Puente-Moncada N, Lilljebjörn H, Cammenga J, Pronk CJ, Lazarevic V, Fioretos T, Hagström-Andersson AK, Woods NB, Järås M. Rodriguez-Zabala M, et al. Among authors: oburoglu l. Blood Adv. 2023 Sep 26;7(18):5382-5395. doi: 10.1182/bloodadvances.2023009967. Blood Adv. 2023. PMID: 37505194 Free PMC article.
Ciclopirox ethanolamine preserves the immature state of human HSCs by mediating intracellular iron content.
Talkhoncheh MS, Baudet A, Ek F, Subramaniam A, Kao YR, Miharada N, Karlsson C, Oburoglu L, Rydström A, Zemaitis K, Alattar AG, Rak J, Pietras K, Olsson R, Will B, Larsson J. Talkhoncheh MS, et al. Among authors: oburoglu l. Blood Adv. 2023 Dec 26;7(24):7407-7417. doi: 10.1182/bloodadvances.2023009844. Blood Adv. 2023. PMID: 37487020 Free PMC article.
An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism.
Gonzalez-Menendez P, Romano M, Yan H, Deshmukh R, Papoin J, Oburoglu L, Daumur M, Dumé AS, Phadke I, Mongellaz C, Qu X, Bories PN, Fontenay M, An X, Dardalhon V, Sitbon M, Zimmermann VS, Gallagher PG, Tardito S, Blanc L, Mohandas N, Taylor N, Kinet S. Gonzalez-Menendez P, et al. Among authors: oburoglu l. Cell Rep. 2021 Feb 2;34(5):108723. doi: 10.1016/j.celrep.2021.108723. Cell Rep. 2021. PMID: 33535038 Free PMC article.
Correction: S100A6 is a critical regulator of hematopoietic stem cells.
Grahn THM, Niroula A, Végvári Á, Oburoglu L, Pertesi M, Warsi S, Safi F, Miharada N, Capellera-Garcia S, Siva K, Liu Y, Rörby E, Nilsson B, Zubarev RA, Karlsson S. Grahn THM, et al. Among authors: oburoglu l. Leukemia. 2020 Dec;34(12):3439. doi: 10.1038/s41375-020-0971-1. Leukemia. 2020. PMID: 32665696 Free PMC article.
S100A6 is a critical regulator of hematopoietic stem cells.
Grahn THM, Niroula A, Végvári Á, Oburoglu L, Pertesi M, Warsi S, Safi F, Miharada N, Garcia SC, Siva K, Liu Y, Rörby E, Nilsson B, Zubarev RA, Karlsson S. Grahn THM, et al. Among authors: oburoglu l. Leukemia. 2020 Dec;34(12):3323-3337. doi: 10.1038/s41375-020-0901-2. Epub 2020 Jun 19. Leukemia. 2020. PMID: 32555370 Free PMC article.
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