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Endogenous Tumor Suppressor microRNA-193b: Therapeutic and Prognostic Value in Acute Myeloid Leukemia.
Bhayadia R, Krowiorz K, Haetscher N, Jammal R, Emmrich S, Obulkasim A, Fiedler J, Schwarzer A, Rouhi A, Heuser M, Wingert S, Bothur S, Döhner K, Mätzig T, Ng M, Reinhardt D, Döhner H, Zwaan CM, van den Heuvel Eibrink M, Heckl D, Fornerod M, Thum T, Humphries RK, Rieger MA, Kuchenbauer F, Klusmann JH. Bhayadia R, et al. Among authors: obulkasim a. J Clin Oncol. 2018 Apr 1;36(10):1007-1016. doi: 10.1200/JCO.2017.75.2204. Epub 2018 Feb 12. J Clin Oncol. 2018. PMID: 29432078
miR-139-5p controls translation in myeloid leukemia through EIF4G2.
Emmrich S, Engeland F, El-Khatib M, Henke K, Obulkasim A, Schöning J, Katsman-Kuipers JE, Michel Zwaan C, Pich A, Stary J, Baruchel A, de Haas V, Reinhardt D, Fornerod M, van den Heuvel-Eibrink MM, Klusmann JH. Emmrich S, et al. Among authors: obulkasim a. Oncogene. 2016 Apr 7;35(14):1822-31. doi: 10.1038/onc.2015.247. Epub 2015 Jul 13. Oncogene. 2016. PMID: 26165837
MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia.
Verboon LJ, Obulkasim A, de Rooij JD, Katsman-Kuipers JE, Sonneveld E, Baruchel A, Trka J, Reinhardt D, Pieters R, Cloos J, Kaspers GJ, Klusmann JH, Zwaan CM, Fornerod M, van den Heuvel-Eibrink MM. Verboon LJ, et al. Among authors: obulkasim a. Oncotarget. 2016 Jul 26;7(30):48412-48422. doi: 10.18632/oncotarget.10270. Oncotarget. 2016. PMID: 27351222 Free PMC article.
Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia.
de Rooij JD, Beuling E, van den Heuvel-Eibrink MM, Obulkasim A, Baruchel A, Trka J, Reinhardt D, Sonneveld E, Gibson BE, Pieters R, Zimmermann M, Zwaan CM, Fornerod M. de Rooij JD, et al. Among authors: obulkasim a. Haematologica. 2015 Sep;100(9):1151-9. doi: 10.3324/haematol.2015.124321. Epub 2015 Jun 11. Haematologica. 2015. PMID: 26069293 Free PMC article. Clinical Trial.
Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.
de Rooij JD, Branstetter C, Ma J, Li Y, Walsh MP, Cheng J, Obulkasim A, Dang J, Easton J, Verboon LJ, Mulder HL, Zimmermann M, Koss C, Gupta P, Edmonson M, Rusch M, Lim JY, Reinhardt K, Pigazzi M, Song G, Yeoh AE, Shih LY, Liang DC, Halene S, Krause DS, Zhang J, Downing JR, Locatelli F, Reinhardt D, van den Heuvel-Eibrink MM, Zwaan CM, Fornerod M, Gruber TA. de Rooij JD, et al. Among authors: obulkasim a. Nat Genet. 2017 Mar;49(3):451-456. doi: 10.1038/ng.3772. Epub 2017 Jan 23. Nat Genet. 2017. PMID: 28112737 Free PMC article.
MN1 overexpression is driven by loss of DNMT3B methylation activity in inv(16) pediatric AML.
Larmonie NSD, Arentsen-Peters TCJM, Obulkasim A, Valerio D, Sonneveld E, Danen-van Oorschot AA, de Haas V, Reinhardt D, Zimmermann M, Trka J, Baruchel A, Pieters R, van den Heuvel-Eibrink MM, Zwaan CM, Fornerod M. Larmonie NSD, et al. Among authors: obulkasim a. Oncogene. 2018 Jan 4;37(1):107-115. doi: 10.1038/onc.2017.293. Epub 2017 Sep 11. Oncogene. 2018. PMID: 28892045
15 results