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Tert-butylhydroquinone abrogates fructose-induced insulin resistance in rats via mitigation of oxidant stress, NFkB-mediated inflammation in the liver but not the skeletal muscle of high fructose drinking rats.
Eleazu CO, Obeten UN, Ozor G, Njemanze CC, Eleazu KC, Egedigwe-Ekeleme AC, Okorie UC, Ogunwa SC, Adeolu AI, Okoh PN, Kalu AO, Onyia CJ, Onyia S, Ossai P, Chikezie CC, Odii BC, Obi V, Igwe VM, Amobi CA, Ugada OJ, Kalu WO, Kanu S. Eleazu CO, et al. Among authors: obeten un. J Food Biochem. 2022 Dec;46(12):e14473. doi: 10.1111/jfbc.14473. Epub 2022 Oct 17. J Food Biochem. 2022. PMID: 36251589
Identification of some bioactive compounds from Trignonella foenumgraecum as possible inhibitors of PPARϒ for diabetes treatment through molecular docking studies, pharmacophore modelling and ADMET profiling: An in-silico study.
Okoh OS, Yakubu A, Adegboyega AE, Uti DE, Obeten UN, Agada SA, Oluwaloni F, Johnson GI, Mela LP, Asomadu RO, Iwaloye O, Johnson TO, Orji OU. Okoh OS, et al. Among authors: obeten un. PLoS One. 2023 May 18;18(5):e0284210. doi: 10.1371/journal.pone.0284210. eCollection 2023. PLoS One. 2023. PMID: 37200359 Free PMC article.