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Identification of an Optimal TLR8 Ligand by Alternating the Position of 2'-O-Ribose Methylation.
Int J Mol Sci. 2022 Sep 22;23(19):11139. doi: 10.3390/ijms231911139.
Int J Mol Sci. 2022.
PMID: 36232437
Free PMC article.
A ribosomal RNA fragment with 2',3'-cyclic phosphate and GTP-binding activity acts as RIG-I ligand.
Jung S, von Thülen T, Yang I, Laukemper V, Rupf B, Janga H, Panagiotidis GD, Schoen A, Nicolai M, Schulte LN, Obermann HL, Weber F, Kaufmann A, Bauer S.
Jung S, et al. Among authors: obermann hl.
Nucleic Acids Res. 2020 Oct 9;48(18):10397-10412. doi: 10.1093/nar/gkaa739.
Nucleic Acids Res. 2020.
PMID: 32946572
Free PMC article.
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RNA-Cholesterol Nanoparticles Function as Potent Immune Activators via TLR7 and TLR8.
Obermann HL, Lederbogen II, Steele J, Dorna J, Sander LE, Engelhardt K, Bakowsky U, Kaufmann A, Bauer S.
Obermann HL, et al.
Front Immunol. 2022 Jan 21;12:658895. doi: 10.3389/fimmu.2021.658895. eCollection 2021.
Front Immunol. 2022.
PMID: 35126343
Free PMC article.
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TLR8 is activated by 5'-methylthioinosine, a Plasmodium falciparum-derived intermediate of the purine salvage pathway.
Köllisch G, Solis FV, Obermann HL, Eckert J, Müller T, Vierbuchen T, Rickmeyer T, Muche S, Przyborski JM, Heine H, Kaufmann A, Baumeister S, Lingelbach K, Bauer S.
Köllisch G, et al. Among authors: obermann hl.
Cell Rep. 2022 Apr 12;39(2):110691. doi: 10.1016/j.celrep.2022.110691.
Cell Rep. 2022.
PMID: 35417716
Free article.
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Toll-like receptor 9, what o'clock is it?
Obermann HL, Bauer S.
Obermann HL, et al.
Immunity. 2012 Feb 24;36(2):159-61. doi: 10.1016/j.immuni.2012.02.003.
Immunity. 2012.
PMID: 22365660
Free article.
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RNA-DNA hybrids and ssDNA differ in intracellular half-life and toll-like receptor 9 activation.
Obermann HL, Eberhardt I, Yu P, Kaufmann A, Bauer S.
Obermann HL, et al.
Immunobiology. 2019 Nov;224(6):843-851. doi: 10.1016/j.imbio.2019.08.001. Epub 2019 Aug 10.
Immunobiology. 2019.
PMID: 31521407
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ADAR1 Is Required for Dendritic Cell Subset Homeostasis and Alveolar Macrophage Function.
Baal N, Cunningham S, Obermann HL, Thomas J, Lippitsch A, Dietert K, Gruber AD, Kaufmann A, Michel G, Nist A, Stiewe T, Rupp O, Goesmann A, Zukunft S, Fleming I, Bein G, Lohmeyer J, Bauer S, Hackstein H.
Baal N, et al. Among authors: obermann hl.
J Immunol. 2019 Feb 15;202(4):1099-1111. doi: 10.4049/jimmunol.1800269. Epub 2019 Jan 16.
J Immunol. 2019.
PMID: 30651342
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IRF9 Prevents CD8+ T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection.
Huber M, Suprunenko T, Ashhurst T, Marbach F, Raifer H, Wolff S, Strecker T, Viengkhou B, Jung SR, Obermann HL, Bauer S, Xu HC, Lang PA, Tom A, Lang KS, King NJC, Campbell IL, Hofer MJ.
Huber M, et al. Among authors: obermann hl.
J Virol. 2017 Oct 27;91(22):e01219-17. doi: 10.1128/JVI.01219-17. Print 2017 Nov 15.
J Virol. 2017.
PMID: 28878077
Free PMC article.
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