Oberhauser B - Search Results

1

A High-Throughput Screening Identifies MICU1 Targeting Compounds.

Di Marco G, Vallese F, Jourde B, Bergsdorf C, Sturlese M, De Mario A, Techer-Etienne V, Haasen D, Oberhauser B, Schleeger S, Minetti G, Moro S, Rizzuto R, De Stefani D, Fornaro M, Mammucari C. Di Marco G, et al. Among authors: oberhauser b. Cell Rep. 2020 Feb 18;30(7):2321-2331.e6. doi: 10.1016/j.celrep.2020.01.081. Cell Rep. 2020. PMID: 32075766 Free PMC article.

2

Orally active 7-substituted (4-benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as active-site inhibitors of sphingosine 1-phosphate lyase for the treatment of multiple sclerosis.

Weiler S, Braendlin N, Beerli C, Bergsdorf C, Schubart A, Srinivas H, Oberhauser B, Billich A. Weiler S, et al. Among authors: oberhauser b. J Med Chem. 2014 Jun 26;57(12):5074-84. doi: 10.1021/jm500338n. Epub 2014 May 21. J Med Chem. 2014. PMID: 24809814

3

Targeting ceramide metabolism with a potent and specific ceramide kinase inhibitor.

Graf C, Klumpp M, Habig M, Rovina P, Billich A, Baumruker T, Oberhauser B, Bornancin F. Graf C, et al. Among authors: oberhauser b. Mol Pharmacol. 2008 Oct;74(4):925-32. doi: 10.1124/mol.108.048652. Epub 2008 Jul 8. Mol Pharmacol. 2008. PMID: 18612076

4

Development of Selective, Orally Active GPR4 Antagonists with Modulatory Effects on Nociception, Inflammation, and Angiogenesis.

Velcicky J, Miltz W, Oberhauser B, Orain D, Vaupel A, Weigand K, Dawson King J, Littlewood-Evans A, Nash M, Feifel R, Loetscher P. Velcicky J, et al. Among authors: oberhauser b. J Med Chem. 2017 May 11;60(9):3672-3683. doi: 10.1021/acs.jmedchem.6b01703. Epub 2017 Apr 26. J Med Chem. 2017. PMID: 28445047

5

Design and synthesis of potent and orally active GPR4 antagonists with modulatory effects on nociception, inflammation, and angiogenesis.

Miltz W, Velcicky J, Dawson J, Littlewood-Evans A, Ludwig MG, Seuwen K, Feifel R, Oberhauser B, Meyer A, Gabriel D, Nash M, Loetscher P. Miltz W, et al. Among authors: oberhauser b. Bioorg Med Chem. 2017 Aug 15;25(16):4512-4525. doi: 10.1016/j.bmc.2017.06.050. Epub 2017 Jun 29. Bioorg Med Chem. 2017. PMID: 28689977

6

Inhibition of vascular endothelial growth factor cotranslational translocation by the cyclopeptolide CAM741.

Harant H, Wolff B, Schreiner EP, Oberhauser B, Hofer L, Lettner N, Maier S, de Vries JE, Lindley IJ. Harant H, et al. Among authors: oberhauser b. Mol Pharmacol. 2007 Jun;71(6):1657-65. doi: 10.1124/mol.107.034249. Epub 2007 Mar 16. Mol Pharmacol. 2007. PMID: 17369307

7

Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy.

Cruz JM, Hupper N, Wilson LS, Concannon JB, Wang Y, Oberhauser B, Patora-Komisarska K, Zhang Y, Glass DJ, Trendelenburg AU, Clarke BA. Cruz JM, et al. Among authors: oberhauser b. J Biol Chem. 2018 Jul 27;293(30):11837-11849. doi: 10.1074/jbc.RA118.002633. Epub 2018 Jun 13. J Biol Chem. 2018. PMID: 29899111 Free PMC article.

8

The translocation inhibitor CAM741 interferes with vascular cell adhesion molecule 1 signal peptide insertion at the translocon.

Harant H, Lettner N, Hofer L, Oberhauser B, de Vries JE, Lindley IJ. Harant H, et al. Among authors: oberhauser b. J Biol Chem. 2006 Oct 13;281(41):30492-502. doi: 10.1074/jbc.M607243200. Epub 2006 Aug 16. J Biol Chem. 2006. PMID: 16914554 Free article.

9

Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1.

Besemer J, Harant H, Wang S, Oberhauser B, Marquardt K, Foster CA, Schreiner EP, de Vries JE, Dascher-Nadel C, Lindley IJ. Besemer J, et al. Among authors: oberhauser b. Nature. 2005 Jul 14;436(7048):290-3. doi: 10.1038/nature03670. Nature. 2005. PMID: 16015337

10

New insights into molecular changes in skeletal muscle aging and disease: Differential alternative splicing and senescence.

Solovyeva EM, Ibebunjo C, Utzinger S, Eash JK, Dunbar A, Naumann U, Zhang Y, Serluca FC, Demirci S, Oberhauser B, Black F, Rausch M, Hoersch S, Meyer AS. Solovyeva EM, et al. Among authors: oberhauser b. Mech Ageing Dev. 2021 Jul;197:111510. doi: 10.1016/j.mad.2021.111510. Epub 2021 May 19. Mech Ageing Dev. 2021. PMID: 34019916 Free article.

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