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There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments.
Rapedius M, Obergrussberger A, Humphries ESA, Scholz S, Rinke-Weiss I, Goetze TA, Brinkwirth N, Rotordam MG, Strassmaier T, Randolph A, Friis S, Liutkute A, Seibertz F, Voigt N, Fertig N. Rapedius M, et al. Among authors: obergrussberger a. Front Mol Neurosci. 2022 Aug 22;15:982316. doi: 10.3389/fnmol.2022.982316. eCollection 2022. Front Mol Neurosci. 2022. PMID: 36072300 Free PMC article.
Automated Patch Clamp Analysis of nAChα7 and Na(V)1.7 Channels.
Obergrussberger A, Haarmann C, Rinke I, Becker N, Guinot D, Brueggemann A, Stoelzle-Feix S, George M, Fertig N. Obergrussberger A, et al. Curr Protoc Pharmacol. 2014 Jun 16;65:11.13.1-48. doi: 10.1002/0471141755.ph1113s65. Curr Protoc Pharmacol. 2014. PMID: 24934604
Novel screening techniques for ion channel targeting drugs.
Obergrussberger A, Stölzle-Feix S, Becker N, Brüggemann A, Fertig N, Möller C. Obergrussberger A, et al. Channels (Austin). 2015;9(6):367-75. doi: 10.1080/19336950.2015.1079675. Epub 2015 Nov 10. Channels (Austin). 2015. PMID: 26556400 Free PMC article. Review.
Safety pharmacology studies using EFP and impedance.
Obergrussberger A, Juhasz K, Thomas U, Stölzle-Feix S, Becker N, Dörr L, Beckler M, Bot C, George M, Fertig N. Obergrussberger A, et al. J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:223-32. doi: 10.1016/j.vascn.2016.04.006. Epub 2016 Apr 12. J Pharmacol Toxicol Methods. 2016. PMID: 27084108
An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery.
Obergrussberger A, Goetze TA, Brinkwirth N, Becker N, Friis S, Rapedius M, Haarmann C, Rinke-Weiß I, Stölzle-Feix S, Brüggemann A, George M, Fertig N. Obergrussberger A, et al. Expert Opin Drug Discov. 2018 Mar;13(3):269-277. doi: 10.1080/17460441.2018.1428555. Epub 2018 Jan 17. Expert Opin Drug Discov. 2018. PMID: 29343120 Review.
A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Time.
Goversen B, Becker N, Stoelzle-Feix S, Obergrussberger A, Vos MA, van Veen TAB, Fertig N, de Boer TP. Goversen B, et al. Among authors: obergrussberger a. Front Physiol. 2018 Jan 19;8:1094. doi: 10.3389/fphys.2017.01094. eCollection 2017. Front Physiol. 2018. PMID: 29403387 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 31963061
19 results