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Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.
Eduful BJ, O'Byrne SN, Temme L, Asquith CRM, Liang Y, Picado A, Pilotte JR, Hossain MA, Wells CI, Zuercher WJ, Catta-Preta CMC, Zonzini Ramos P, Santiago AS, Couñago RM, Langendorf CG, Nay K, Oakhill JS, Pulliam TL, Lin C, Awad D, Willson TM, Frigo DE, Scott JW, Drewry DH. Eduful BJ, et al. Among authors: oakhill js. J Med Chem. 2021 Aug 12;64(15):10849-10877. doi: 10.1021/acs.jmedchem.0c02274. Epub 2021 Jul 15. J Med Chem. 2021. PMID: 34264658 Free PMC article.
AMPK structure and regulation from three angles.
Kemp BE, Oakhill JS, Scott JW. Kemp BE, et al. Among authors: oakhill js. Structure. 2007 Oct;15(10):1161-3. doi: 10.1016/j.str.2007.09.006. Structure. 2007. PMID: 17937905 Free article. No abstract available.
Structure and function of AMP-activated protein kinase.
Oakhill JS, Scott JW, Kemp BE. Oakhill JS, et al. Acta Physiol (Oxf). 2009 May;196(1):3-14. doi: 10.1111/j.1748-1716.2009.01977.x. Epub 2009 Feb 20. Acta Physiol (Oxf). 2009. PMID: 19245650 Review.
AMPK/SNF1 structure: a menage a trois of energy-sensing.
Scott JW, Oakhill JS, van Denderen BJ. Scott JW, et al. Among authors: oakhill js. Front Biosci (Landmark Ed). 2009 Jan 1;14(2):596-610. doi: 10.2741/3266. Front Biosci (Landmark Ed). 2009. PMID: 19273088 Free article. Review.
ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.
Scott JW, Oakhill JS, Ling NX, Langendorf CG, Foitzik RC, Kemp BE, Issinger OG. Scott JW, et al. Among authors: oakhill js. Biochem Biophys Res Commun. 2014 Jan 10;443(2):435-40. doi: 10.1016/j.bbrc.2013.11.130. Epub 2013 Dec 8. Biochem Biophys Res Commun. 2014. PMID: 24332941
79 results