Oakey L - Search Results

1

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD⁺ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures.

Elhassan YS, Kluckova K, Fletcher RS, Schmidt MS, Garten A, Doig CL, Cartwright DM, Oakey L, Burley CV, Jenkinson N, Wilson M, Lucas SJE, Akerman I, Seabright A, Lai YC, Tennant DA, Nightingale P, Wallis GA, Manolopoulos KN, Brenner C, Philp A, Lavery GG. Elhassan YS, et al. Among authors: oakey l. Cell Rep. 2019 Aug 13;28(7):1717-1728.e6. doi: 10.1016/j.celrep.2019.07.043. Cell Rep. 2019. PMID: 31412242 Free PMC article. Clinical Trial.

2

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.

Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. Fletcher RS, et al. Among authors: oakey la. Mol Metab. 2017 May 29;6(8):819-832. doi: 10.1016/j.molmet.2017.05.011. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752046 Free PMC article.

3

Induction of the nicotinamide riboside kinase NAD⁺ salvage pathway in a model of sarcoplasmic reticulum dysfunction.

Doig CL, Zielinska AE, Fletcher RS, Oakey LA, Elhassan YS, Garten A, Cartwright D, Heising S, Alsheri A, Watson DG, Prehn C, Adamski J, Tennant DA, Lavery GG. Doig CL, et al. Among authors: oakey la. Skelet Muscle. 2020 Feb 19;10(1):5. doi: 10.1186/s13395-019-0216-z. Skelet Muscle. 2020. PMID: 32075690 Free PMC article.

4

Nicotinamide riboside has minimal impact on energy metabolism in mouse models of mild obesity.

Cartwright DM, Oakey LA, Fletcher RS, Doig CL, Heising S, Larner DP, Nasteska D, Berry CE, Heaselgrave SR, Ludwig C, Hodson DJ, Lavery GG, Garten A. Cartwright DM, et al. Among authors: oakey la. J Endocrinol. 2021 Sep 9;251(1):111-123. doi: 10.1530/JOE-21-0123. J Endocrinol. 2021. PMID: 34370682 Free PMC article.

5

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD ⁺ depletion.

Oakey LA, Fletcher RS, Elhassan YS, Cartwright DM, Doig CL, Garten A, Thakker A, Maddocks ODK, Zhang T, Tennant DA, Ludwig C, Lavery GG. Oakey LA, et al. Wellcome Open Res. 2019 Sep 17;3:147. doi: 10.12688/wellcomeopenres.14898.2. eCollection 2018. Wellcome Open Res. 2019. PMID: 30607371 Free PMC article.

6

Fundamental differences in bioaffinity of amino acid dehydrogenases for N6- and S6-linked immobilized cofactors using kinetic-based enzyme-capture strategies.

Forde J, Oakey L, Jennings L, Mulcahy P. Forde J, et al. Among authors: oakey l. Anal Biochem. 2005 Mar 1;338(1):102-12. doi: 10.1016/j.ab.2004.11.016. Anal Biochem. 2005. PMID: 15707940

7

Immobilized cofactor derivatives for kinetic-based enzyme capture strategies: direct coupling of NAD(P)+.

Oakey L, Mulcahy P. Oakey L, et al. Anal Biochem. 2004 Dec 15;335(2):316-25. doi: 10.1016/j.ab.2004.08.036. Anal Biochem. 2004. PMID: 15556571

8

Effect of accessible immobilized NAD(+) concentration on the bioaffinity chromatographic behavior of NAD(+)-dependent dehydrogenases using the kinetic locking-on strategy.

Mulcahy P, O'Flaherty M, McMahon M, Oakey L. Mulcahy P, et al. Among authors: oakey l. Protein Expr Purif. 1999 Jul;16(2):261-75. doi: 10.1006/prep.1999.1050. Protein Expr Purif. 1999. PMID: 10419823

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