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Deubiquitinases in muscle physiology and disorders.
Olie CS, O'Brien DP, Jones HBL, Liang Z, Damianou A, Sur-Erdem I, Pinto-Fernández A, Raz V, Kessler BM. Olie CS, et al. Among authors: o brien dp. Biochem Soc Trans. 2024 May 8:BST20230562. doi: 10.1042/BST20230562. Online ahead of print. Biochem Soc Trans. 2024. PMID: 38716888
Mycobacterium ulcerans challenge strain selection for a Buruli ulcer controlled human infection model.
Muhi S, Buultjens AH, Porter JL, Marshall JL, Doerflinger M, Pidot SJ, O'Brien DP, Johnson PDR, Lavender CJ, Globan M, McCarthy J, Osowicki J, Stinear TP. Muhi S, et al. Among authors: o brien dp. PLoS Negl Trop Dis. 2024 May 3;18(5):e0011979. doi: 10.1371/journal.pntd.0011979. eCollection 2024 May. PLoS Negl Trop Dis. 2024. PMID: 38701090 Free PMC article.
Tau depletion in human neurons mitigates Aβ-driven toxicity.
Ng B, Vowles J, Bertherat F, Abey A, Kilfeather P, Beccano-Kelly D, Stefana MI, O'Brien DP, Bengoa-Vergniory N, Carling PJ, Todd JA, Caffrey TM, Connor-Robson N, Cowley SA, Wade-Martins R. Ng B, et al. Among authors: o brien dp. Mol Psychiatry. 2024 Feb 15. doi: 10.1038/s41380-024-02463-2. Online ahead of print. Mol Psychiatry. 2024. PMID: 38361127
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.
Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, Sapmaz A. Gan J, et al. Among authors: o brien dp. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2315163120. doi: 10.1073/pnas.2315163120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055744
Effectiveness of community-based oral antiviral treatments against severe COVID-19 outcomes in people 70 years and over in Victoria, Australia, 2022: an observational study.
Van Heer C, Majumdar SS, Parta I, Martinie M, Dawson R, West D, Hewett L, Lister D, Sutton B, O'Brien DP, Cowie BC. Van Heer C, et al. Among authors: o brien dp. Lancet Reg Health West Pac. 2023 Oct 3;41:100917. doi: 10.1016/j.lanwpc.2023.100917. eCollection 2023 Dec. Lancet Reg Health West Pac. 2023. PMID: 37927380 Free PMC article.
370 results