O'Sullivan RJ - Search Results

1

Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA.

Rose AM, Goncalves T, Cunniffe S, Geiller HEB, Kent T, Shepherd S, Ratnaweera M, O'Sullivan RJ, Gibbons RJ, Clynes D. Rose AM, et al. Among authors: o sullivan rj. Nucleic Acids Res. 2023 Jul 21;51(13):6509-6527. doi: 10.1093/nar/gkad150. Nucleic Acids Res. 2023. PMID: 36940725 Free PMC article.

2

The human Shu complex functions with PDS5B and SPIDR to promote homologous recombination.

Martino J, Brunette GJ, Barroso-González J, Moiseeva TN, Smith CM, Bakkenist CJ, O'Sullivan RJ, Bernstein KA. Martino J, et al. Nucleic Acids Res. 2019 Nov 4;47(19):10151-10165. doi: 10.1093/nar/gkz738. Nucleic Acids Res. 2019. PMID: 31665741 Free PMC article.

3

Alternative Lengthening of Telomeres: Building Bridges To Connect Chromosome Ends.

Hoang SM, O'Sullivan RJ. Hoang SM, et al. Trends Cancer. 2020 Mar;6(3):247-260. doi: 10.1016/j.trecan.2019.12.009. Epub 2020 Jan 23. Trends Cancer. 2020. PMID: 32101727 Free PMC article. Review.

4

New twists to the ALTernative endings at telomeres.

Bhargava R, Lynskey ML, O'Sullivan RJ. Bhargava R, et al. DNA Repair (Amst). 2022 Jul;115:103342. doi: 10.1016/j.dnarep.2022.103342. Epub 2022 May 13. DNA Repair (Amst). 2022. PMID: 35588569 Free PMC article. Review.

5

Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors.

Singhi AD, Liu TC, Roncaioli JL, Cao D, Zeh HJ, Zureikat AH, Tsung A, Marsh JW, Lee KK, Hogg ME, Bahary N, Brand RE, McGrath KM, Slivka A, Cressman KL, Fuhrer K, O'Sullivan RJ. Singhi AD, et al. Clin Cancer Res. 2017 Jan 15;23(2):600-609. doi: 10.1158/1078-0432.CCR-16-1113. Epub 2016 Jul 12. Clin Cancer Res. 2017. PMID: 27407094 Free PMC article.

6

Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres.

Garcia-Exposito L, Bournique E, Bergoglio V, Bose A, Barroso-Gonzalez J, Zhang S, Roncaioli JL, Lee M, Wallace CT, Watkins SC, Opresko PL, Hoffmann JS, O'Sullivan RJ. Garcia-Exposito L, et al. Cell Rep. 2016 Nov 8;17(7):1858-1871. doi: 10.1016/j.celrep.2016.10.048. Cell Rep. 2016. PMID: 27829156 Free PMC article.

7

TZAP-ing telomeres down to size.

Garcia-Exposito L, O'Sullivan RJ. Garcia-Exposito L, et al. EMBO Rep. 2017 Jun;18(6):861-863. doi: 10.15252/embr.201744354. Epub 2017 May 12. EMBO Rep. 2017. PMID: 28500256 Free PMC article.

8

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.

Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, de Vitis M, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ. Barroso-González J, et al. Mol Cell. 2019 Oct 3;76(1):11-26.e7. doi: 10.1016/j.molcel.2019.06.043. Epub 2019 Aug 7. Mol Cell. 2019. PMID: 31400850 Free PMC article.

9

TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells.

Xu M, Senanayaka D, Zhao R, Chigumira T, Tripathi A, Tones J, Lackner RM, Wondisford AR, Moneysmith LN, Hirschi A, Craig S, Alishiri S, O'Sullivan RJ, Chenoweth DM, Reiter NJ, Zhang H. Xu M, et al. Among authors: o sullivan rj. Nat Commun. 2024 Mar 9;15(1):2165. doi: 10.1038/s41467-024-46509-z. Nat Commun. 2024. PMID: 38461301 Free PMC article.

10

Extrachromosomal telomere DNA derived from excessive strand displacements.

Lee J, Lee J, Sohn EJ, Taglialatela A, O'Sullivan RJ, Ciccia A, Min J. Lee J, et al. Among authors: o sullivan rj. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2318438121. doi: 10.1073/pnas.2318438121. Epub 2024 May 2. Proc Natl Acad Sci U S A. 2024. PMID: 38696464

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