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Enhanced pyrazolopyrimidinones cytotoxicity against glioblastoma cells activated by ROS-Generating cold atmospheric plasma.
He Z, Charleton C, Devine RW, Kelada M, Walsh JMD, Conway GE, Gunes S, Mondala JRM, Tian F, Tiwari B, Kinsella GK, Malone R, O'Shea D, Devereux M, Wang W, Cullen PJ, Stephens JC, Curtin JF. He Z, et al. Eur J Med Chem. 2021 Nov 15;224:113736. doi: 10.1016/j.ejmech.2021.113736. Epub 2021 Aug 2. Eur J Med Chem. 2021. PMID: 34384944 Free article.
Influence of molecular weight fractionation on the antimicrobial and anticancer properties of a fucoidan rich-extract from the macroalgae Fucus vesiculosus.
Cabral EM, Mondala JRM, Oliveira M, Przyborska J, Fitzpatrick S, Rai DK, Sivagnanam SP, Garcia-Vaquero M, O'Shea D, Devereux M, Tiwari BK, Curtin J. Cabral EM, et al. Int J Biol Macromol. 2021 Sep 1;186:994-1002. doi: 10.1016/j.ijbiomac.2021.06.182. Epub 2021 Jun 30. Int J Biol Macromol. 2021. PMID: 34216667 Free article.
Copper(II) complexes of salicylic acid combining superoxide dismutase mimetic properties with DNA binding and cleaving capabilities display promising chemotherapeutic potential with fast acting in vitro cytotoxicity against cisplatin sensitive and resistant cancer cell lines.
O'Connor M, Kellett A, McCann M, Rosair G, McNamara M, Howe O, Creaven BS, McClean S, Kia AF, O'Shea D, Devereux M. O'Connor M, et al. J Med Chem. 2012 Mar 8;55(5):1957-68. doi: 10.1021/jm201041d. Epub 2012 Feb 28. J Med Chem. 2012. PMID: 22313179
Water-soluble and photo-stable silver(I) dicarboxylate complexes containing 1,10-phenanthroline ligands: Antimicrobial and anticancer chemotherapeutic potential, DNA interactions and antioxidant activity.
Thornton L, Dixit V, Assad LO, Ribeiro TP, Queiroz DD, Kellett A, Casey A, Colleran J, Pereira MD, Rochford G, McCann M, O'Shea D, Dempsey R, McClean S, Kia AF, Walsh M, Creaven B, Howe O, Devereux M. Thornton L, et al. J Inorg Biochem. 2016 Jun;159:120-32. doi: 10.1016/j.jinorgbio.2016.02.024. Epub 2016 Mar 2. J Inorg Biochem. 2016. PMID: 26986979
Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen donor ligands.
Devereux M, O Shea D, Kellett A, McCann M, Walsh M, Egan D, Deegan C, Kedziora K, Rosair G, Müller-Bunz H. Devereux M, et al. J Inorg Biochem. 2007 Jun;101(6):881-92. doi: 10.1016/j.jinorgbio.2007.02.002. Epub 2007 Feb 14. J Inorg Biochem. 2007. PMID: 17397929
Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dmepda)(bipy)(EtOH)](2). 4EtOH (bipy = 2,2'Bipyridine).
Devereux M, McCann M, O'shea D, O'connor M, Kiely E, McKee V, Naughton D, Fisher A, Kellett A, Walsh M, Egan D, Deegan C. Devereux M, et al. Bioinorg Chem Appl. 2006;2006:80283. doi: 10.1155/BCA/2006/80283. Epub 2006 Mar 20. Bioinorg Chem Appl. 2006. PMID: 17497019 Free PMC article.
646 results