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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1930 1
1953 1
1963 3
1964 1
1965 1
1966 1
1967 2
1969 3
1970 2
1972 2
1973 2
1974 2
1976 1
1978 2
1979 2
1980 2
1982 5
1983 1
1984 3
1985 6
1986 3
1987 5
1988 5
1989 3
1991 1
1992 3
1993 2
1994 10
1995 9
1996 12
1997 11
1998 5
1999 13
2000 15
2001 9
2002 7
2003 19
2004 11
2005 7
2006 11
2007 13
2008 16
2009 18
2010 22
2011 18
2012 16
2013 12
2014 18
2015 23
2016 11
2017 19
2018 34
2019 48
2020 34
2021 34
2022 43
2023 29
2024 13

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Publication date

Search Results

561 results

Results by year

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Page 1
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity.
Jacob F, Salinas RD, Zhang DY, Nguyen PTT, Schnoll JG, Wong SZH, Thokala R, Sheikh S, Saxena D, Prokop S, Liu DA, Qian X, Petrov D, Lucas T, Chen HI, Dorsey JF, Christian KM, Binder ZA, Nasrallah M, Brem S, O'Rourke DM, Ming GL, Song H. Jacob F, et al. Among authors: o rourke dm. Cell. 2020 Jan 9;180(1):188-204.e22. doi: 10.1016/j.cell.2019.11.036. Epub 2019 Dec 26. Cell. 2020. PMID: 31883794 Free PMC article.
Nontraditional Species.
O’Rourke DP, Cox JD, Baumann DP. O’Rourke DP, et al. In: Weichbrod RH, Thompson GA, Norton JN, editors. Management of Animal Care and Use Programs in Research, Education, and Testing. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 25. In: Weichbrod RH, Thompson GA, Norton JN, editors. Management of Animal Care and Use Programs in Research, Education, and Testing. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 25. PMID: 29787227 Free Books & Documents. Review.
CAR T Cells.
Tudor T, Binder ZA, O'Rourke DM. Tudor T, et al. Among authors: o rourke dm. Neurosurg Clin N Am. 2021 Apr;32(2):249-263. doi: 10.1016/j.nec.2020.12.005. Epub 2021 Feb 18. Neurosurg Clin N Am. 2021. PMID: 33781506 Review.
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
O'Rourke DM, Nasrallah MP, Desai A, Melenhorst JJ, Mansfield K, Morrissette JJD, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey SF, Navenot JM, Zheng Z, Levine BL, Okada H, June CH, Brogdon JL, Maus MV. O'Rourke DM, et al. Sci Transl Med. 2017 Jul 19;9(399):eaaa0984. doi: 10.1126/scitranslmed.aaa0984. Sci Transl Med. 2017. PMID: 28724573 Free PMC article. Clinical Trial.
Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors.
Yin Y, Rodriguez JL, Li N, Thokala R, Nasrallah MP, Hu L, Zhang L, Zhang JV, Logun MT, Kainth D, Haddad L, Zhao Y, Wu T, Johns EX, Long Y, Liang H, Qi J, Zhang X, Binder ZA, Lin Z, O'Rourke DM. Yin Y, et al. Among authors: o rourke dm. Mol Ther. 2022 Jul 6;30(7):2537-2553. doi: 10.1016/j.ymthe.2022.05.011. Epub 2022 May 14. Mol Ther. 2022. PMID: 35570396 Free PMC article.
Optimizing CAR-T Therapy for Glioblastoma.
Tang OY, Binder ZA, O'Rourke DM, Bagley SJ. Tang OY, et al. Among authors: o rourke dm. Mol Diagn Ther. 2023 Nov;27(6):643-660. doi: 10.1007/s40291-023-00671-0. Epub 2023 Sep 12. Mol Diagn Ther. 2023. PMID: 37700186 Review.
IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, Mellinghoff IK, Thompson CB. Lu C, et al. Among authors: o rourke dm. Nature. 2012 Feb 15;483(7390):474-8. doi: 10.1038/nature10860. Nature. 2012. PMID: 22343901 Free PMC article.
Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results.
Bagley SJ, Logun M, Fraietta JA, Wang X, Desai AS, Bagley LJ, Nabavizadeh A, Jarocha D, Martins R, Maloney E, Lledo L, Stein C, Marshall A, Leskowitz R, Jadlowsky JK, Christensen S, Oner BS, Plesa G, Brennan A, Gonzalez V, Chen F, Sun Y, Gladney W, Barrett D, Nasrallah MP, Hwang WT, Ming GL, Song H, Siegel DL, June CH, Hexner EO, Binder ZA, O'Rourke DM. Bagley SJ, et al. Among authors: o rourke dm. Nat Med. 2024 Mar 13. doi: 10.1038/s41591-024-02893-z. Online ahead of print. Nat Med. 2024. PMID: 38480922
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial.
Weller M, Butowski N, Tran DD, Recht LD, Lim M, Hirte H, Ashby L, Mechtler L, Goldlust SA, Iwamoto F, Drappatz J, O'Rourke DM, Wong M, Hamilton MG, Finocchiaro G, Perry J, Wick W, Green J, He Y, Turner CD, Yellin MJ, Keler T, Davis TA, Stupp R, Sampson JH; ACT IV trial investigators. Weller M, et al. Among authors: o rourke dm. Lancet Oncol. 2017 Oct;18(10):1373-1385. doi: 10.1016/S1470-2045(17)30517-X. Epub 2017 Aug 23. Lancet Oncol. 2017. PMID: 28844499 Free article. Clinical Trial.
EGFR, the Lazarus target for precision oncology in glioblastoma.
Lin B, Ziebro J, Smithberger E, Skinner KR, Zhao E, Cloughesy TF, Binder ZA, O'Rourke DM, Nathanson DA, Furnari FB, Miller CR. Lin B, et al. Among authors: o rourke dm. Neuro Oncol. 2022 Dec 1;24(12):2035-2062. doi: 10.1093/neuonc/noac204. Neuro Oncol. 2022. PMID: 36125064 Free PMC article. Review.
561 results