O'Neill LAJ - Search Results

1

Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses.

Lundahl MLE, Mitermite M, Ryan DG, Case S, Williams NC, Yang M, Lynch RI, Lagan E, Lebre FM, Gorman AL, Stojkovic B, Bracken AP, Frezza C, Sheedy FJ, Scanlan EM, O'Neill LAJ, Gordon SV, Lavelle EC. Lundahl MLE, et al. Elife. 2022 Sep 29;11:e74690. doi: 10.7554/eLife.74690. Elife. 2022. PMID: 36173104 Free PMC article.

2

The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling.

Sheedy FJ, O'Neill LA. Sheedy FJ, et al. J Leukoc Biol. 2007 Aug;82(2):196-203. doi: 10.1189/jlb.1206750. Epub 2007 Apr 20. J Leukoc Biol. 2007. PMID: 17449723 Review.

3

The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to, or severity of, rheumatoid arthritis.

Sheedy FJ, Marinou I, O'Neill LA, Wilson AG. Sheedy FJ, et al. Ann Rheum Dis. 2008 Sep;67(9):1328-31. doi: 10.1136/ard.2007.083337. Epub 2008 Jan 7. Ann Rheum Dis. 2008. PMID: 18180278

4

Adding fuel to fire: microRNAs as a new class of mediators of inflammation.

Sheedy FJ, O'Neill LA. Sheedy FJ, et al. Ann Rheum Dis. 2008 Dec;67 Suppl 3:iii50-5. doi: 10.1136/ard.2008.100289. Ann Rheum Dis. 2008. PMID: 19022814 Review.

5

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.

Sharp FA, Ruane D, Claass B, Creagh E, Harris J, Malyala P, Singh M, O'Hagan DT, Pétrilli V, Tschopp J, O'Neill LA, Lavelle EC. Sharp FA, et al. Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):870-5. doi: 10.1073/pnas.0804897106. Epub 2009 Jan 12. Proc Natl Acad Sci U S A. 2009. PMID: 19139407 Free PMC article.

6

The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis.

Lavelle EC, Murphy C, O'Neill LA, Creagh EM. Lavelle EC, et al. Mucosal Immunol. 2010 Jan;3(1):17-28. doi: 10.1038/mi.2009.124. Epub 2009 Nov 4. Mucosal Immunol. 2010. PMID: 19890268 Free PMC article. Review.

7

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21.

Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, Johnson DS, Chen Y, O'Neill LA. Sheedy FJ, et al. Nat Immunol. 2010 Feb;11(2):141-7. doi: 10.1038/ni.1828. Epub 2009 Nov 29. Nat Immunol. 2010. PMID: 19946272

8

IL-10 inhibits miR-155 induction by toll-like receptors.

McCoy CE, Sheedy FJ, Qualls JE, Doyle SL, Quinn SR, Murray PJ, O'Neill LA. McCoy CE, et al. J Biol Chem. 2010 Jul 2;285(27):20492-8. doi: 10.1074/jbc.M110.102111. Epub 2010 Apr 30. J Biol Chem. 2010. PMID: 20435894 Free PMC article.

9

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.

Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nuñez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA. Masters SL, et al. Nat Immunol. 2010 Oct;11(10):897-904. doi: 10.1038/ni.1935. Epub 2010 Sep 12. Nat Immunol. 2010. PMID: 20835230 Free PMC article.

10

MicroRNAs: the fine-tuners of Toll-like receptor signalling.

O'Neill LA, Sheedy FJ, McCoy CE. O'Neill LA, et al. Nat Rev Immunol. 2011 Mar;11(3):163-75. doi: 10.1038/nri2957. Epub 2011 Feb 18. Nat Rev Immunol. 2011. PMID: 21331081 Review.

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