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The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.
d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ. d'Adhemar CJ, et al. PLoS One. 2014 Jun 30;9(6):e100816. doi: 10.1371/journal.pone.0100816. eCollection 2014. PLoS One. 2014. PMID: 24977712 Free PMC article.
Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.
To EE, Vlahos R, Luong R, Halls ML, Reading PC, King PT, Chan C, Drummond GR, Sobey CG, Broughton BRS, Starkey MR, van der Sluis R, Lewin SR, Bozinovski S, O'Neill LAJ, Quach T, Porter CJH, Brooks DA, O'Leary JJ, Selemidis S. To EE, et al. Nat Commun. 2017 Jul 12;8(1):69. doi: 10.1038/s41467-017-00057-x. Nat Commun. 2017. PMID: 28701733 Free PMC article.
MyD88 is an essential component of retinoic acid-induced differentiation in human pluripotent embryonal carcinoma cells.
Sulaiman G, Cooke A, Ffrench B, Gasch C, Abdullai OA, O'Connor K, Elbaruni S, Blackshields G, Spillane C, Keegan H, McEneaney V, Knittel R, Rogers A, Jeffery IB, Doyle B, Bates M, d'Adhemar C, Lee MY, Campbell EL, Moynagh PN, Higgins DG, O'Toole S, O'Neill L, O'Leary JJ, Gallagher MF. Sulaiman G, et al. Cell Death Differ. 2017 Nov;24(11):1975-1986. doi: 10.1038/cdd.2017.124. Epub 2017 Sep 8. Cell Death Differ. 2017. PMID: 28885616 Free PMC article.
Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice.
Liong S, Oseghale O, To EE, Brassington K, Erlich JR, Luong R, Liong F, Brooks R, Martin C, O'Toole S, Vinh A, O'Neill LAJ, Bozinovski S, Vlahos R, Papagianis PC, O'Leary JJ, Brooks DA, Selemidis S. Liong S, et al. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24964-24973. doi: 10.1073/pnas.2006905117. Epub 2020 Sep 21. Proc Natl Acad Sci U S A. 2020. PMID: 32958663 Free PMC article.
Altered inflammasome activation in neonatal encephalopathy persists in childhood.
Kelly LA, O'Dea MI, Zareen Z, Melo AM, McKenna E, Strickland T, McEneaney V, Donoghue V, Boylan G, Sweetman D, Butler J, Vavasseur C, Miletin J, El-Khuffash AF, O'Neill LAJ, O'Leary JJ, Molloy EJ. Kelly LA, et al. Clin Exp Immunol. 2021 Jul;205(1):89-97. doi: 10.1111/cei.13598. Epub 2021 May 2. Clin Exp Immunol. 2021. PMID: 33768526 Free PMC article.
Biochemistry: succinate strikes.
O'Neill LA. O'Neill LA. Nature. 2014 Nov 20;515(7527):350-1. doi: 10.1038/nature13941. Epub 2014 Nov 5. Nature. 2014. PMID: 25383526 No abstract available.
436 results