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Hexokinases inhibit death receptor-dependent apoptosis on the mitochondria.
Lauterwasser J, Fimm-Todt F, Oelgeklaus A, Schreiner A, Funk K, Falquez-Medina H, Klesse R, Jahreis G, Zerbes RM, O'Neill K, van der Laan M, Luo X, Edlich F. Lauterwasser J, et al. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2021175118. doi: 10.1073/pnas.2021175118. Proc Natl Acad Sci U S A. 2021. PMID: 34385311 Free PMC article.
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition.
Roca-Portoles A, Rodriguez-Blanco G, Sumpton D, Cloix C, Mullin M, Mackay GM, O'Neill K, Lemgruber L, Luo X, Tait SWG. Roca-Portoles A, et al. Cell Death Dis. 2020 Aug 13;11(8):616. doi: 10.1038/s41419-020-02867-2. Cell Death Dis. 2020. PMID: 32792521 Free PMC article.
799 results